Rapid, automated nerve histomorphometry through open-source artificial intelligence

SC Daeschler, MH Bourget, D Derakhshan… - Scientific Reports, 2022 - nature.com
We aimed to develop and validate a deep learning model for automated segmentation and
histomorphometry of myelinated peripheral nerve fibers from light microscopic images. A …

[HTML][HTML] The genetics of trichotillomania and excoriation disorder: A systematic review

M Reid, A Lin, LC Farhat, TV Fernandez… - Comprehensive …, 2024 - Elsevier
Background Trichotillomania (TTM) and excoriation disorder (ED) are impairing obsessive-
compulsive related disorders that are common in the general population and for which there …

Importin 13-dependent axon diameter growth regulates conduction speeds along myelinated CNS axons

JM Bin, D Suminaite, SK Benito-Kwiecinski… - Nature …, 2024 - nature.com
Axon diameter influences the conduction properties of myelinated axons, both directly, and
indirectly through effects on myelin. However, we have limited understanding of …

The Sapap3−/− mouse reconsidered as a comorbid model expressing a spectrum of pathological repetitive behaviours

H Lamothe, C Schreiweis… - Translational …, 2023 - nature.com
Symptom comorbidity is present amongst neuropsychiatric disorders with repetitive
behaviours, complicating clinical diagnosis and impeding appropriate treatments. This is of …

SAPAP scaffold proteins: from synaptic function to neuropsychiatric disorders

Y Bai, H Wang, C Li - Cells, 2022 - mdpi.com
Excitatory (glutamatergic) synaptic transmission underlies many aspects of brain activity and
the genesis of normal human behavior. The postsynaptic scaffolding proteins SAP90/PSD …

Cognitive and Behavioral Patterns across Psychiatric Conditions

R Admon, O Klavir - Brain Sciences, 2021 - mdpi.com
Psychiatric conditions represent a highly heterogeneous group of disorders associated with
chronic distress and a sharp decline in quality of life. All psychiatric conditions involve …