Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

Regulation of cell mortality for disease treatment has been the focus of research. Ferroptosis
is an iron-dependent regulated cell death whose mechanism has been extensively studied …

The serine-glycine-one-carbon (SGOC) metabolic pathway is critical for DNA methylation,
histone methylation, and redox homeostasis, in addition to protein, lipid, and nucleotide …

Dysregulation of ferroptosis is involved in breast cancer progression and therapeutic
responses. Inducing ferroptosis can be a potential therapeutic strategy for breast cancer …

Human ALDH comprise 19 subfamilies in which ALDH1A1, ALDH1A3, ALDH3A1,
ALDH5A1, ALDH7A1, and ALDH18A1 are implicated in CSC. Studies have shown that …

Alzheimer's disease (AD) is characterized by the presence of β-amyloid plaques (Aβ) and
neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is …

Most cancer-related deaths are caused by the metastases, which commonly develop at
multiple organ sites including the brain, bone, and lungs. Despite longstanding observations …

Ferroptosis, a unique form of regulated necrotic cell death, is caused by excessive iron-
dependent lipid peroxidation. However, the underlying mechanisms driving ferroptosis in …

Cancer metabolism mainly includes carbohydrate, amino acid and lipid metabolism, each of
which can be reprogrammed. These processes interact with each other to adapt to the …

The nexus of advanced technology and medical therapeutics has ushered in a
transformative epoch in contemporary medicine. Within this arena, Magnetic Resonance …