[HTML][HTML] Advances in immune regulation of the G protein-coupled estrogen receptor

H Dong, X Zeng, J Xu, C He, Z Sun, L Liu… - International …, 2024 - Elsevier
Estrogen and related receptors have been shown to have a significant impact on human
development, reproduction, metabolism and immune regulation and to play a critical role in …

The G Protein-Coupled Estrogen Receptor GPER in the Development and Progression of Cancer

L Torres-López, M Olivas-Aguirre, O Dobrovinskaya - Receptors, 2024 - mdpi.com
The high incidence of cancer and the prevalence of chemoresistance are serious problems
worldwide, underscoring the urgency of novel research focused on understanding the …

G Protein-Coupled Estrogen Receptor-Mediated Anti-Inflammatory and Mucosal Healing Activity of a Trimethylpyridinol Analogue in Inflammatory Bowel Disease

BP Awasthi, P Chaudhary, D Lim, K Yadav… - Journal of Medicinal …, 2024 - ACS Publications
Inflammatory bowel disease (IBD) is characterized by abnormal immune responses,
including elevated proinflammatory cytokines, such as tumor necrosis factor-α (TNFα) and …

LNS8801 inhibits Acute Myeloid Leukemia by inducing the production of reactive oxygen species and activating the endoplasmic reticulum stress pathway

I Lee, M Doepner, J Weissenrieder, AD Majer… - Cancer Research …, 2023 - AACR
Despite recent therapeutic advances, the 5-year survival rate for adults with acute myeloid
leukemia (AML) is poor and standard-of-care chemotherapy is associated with significant …

GPER1 Activation Exerts Anti-Tumor Activity in Multiple Myeloma

ME Gallo Cantafio, R Torcasio, F Scionti, M Mesuraca… - Cells, 2023 - mdpi.com
G protein-coupled estrogen receptor 1 (GPER1) activation is emerging as a promising
therapeutic strategy against several cancer types. While GPER targeting has been widely …

[PDF][PDF] G 蛋白偶联雌激素受体在免疫调节中作用的研究进展

曾小强, 周菁, 黄晏骁, 徐佳伟, 徐家乐, 余腾骅 - 中国普通外科杂志, 2024 - zpwz.net
摘要近年来研究发现, G 蛋白偶联雌激素受体(GPER) 不同于传统的核受体,
是第三种独立作用的雌激素受体, 它属于七次跨膜的G 蛋白偶联受体(GPCR) 家族成员 …

Molecular characterization of the dual effect of the GPER agonist G-1 in glioblastoma

A Hirtz, Y Bailly, F Rech, J Pierson, H Dumond… - International Journal of …, 2022 - mdpi.com
Glioblastoma (GBM) is the most common primary brain tumor in adults. Despite conventional
treatment, consisting of a chirurgical resection followed by concomitant radio …

Význam estrogenového receptoru spřaženého s G proteinem (GPER) pro rakovinu prsu

A Říhová - 2024 - dspace.cuni.cz
Rakovina prsu představuje nejčastěji diagnostikovanou formu maligního onemocnění u žen.
Její progrese je ovlivněna steroidním hormonem estrogenem, který působí prostřednictvím …

Emerging Trends on the Gper in the Last 30 Years: A Bibliometric Study

J Xu, C Yu, X Li, S Xu, L Tang, X Zeng, Z Sun… - Available at SSRN … - papers.ssrn.com
This study aims to conduct a bibliometric evaluation of GPER-related research, analyzing its
distribution patterns and research frontiers worldwide, and providing directions for future …