ABSTRACT A substantial proportion of risk for Parkinson's disease (PD) is driven by
genetics. Progress in understanding the genetic basis of PD has been significant. So far …

Context-dependent biological variation presents a unique challenge to the reproducibility of
results in experimental animal research, because organisms' responses to experimental …

Plants frequently have to weather both biotic and abiotic stressors, and have evolved
sophisticated adaptation and defense mechanisms. In recent years, chromatin modifications …

The epigenome orchestrates genome accessibility, functionality, and three-dimensional
structure. Because epigenetic variation can impact transcription and thus phenotypes, it may …

Since the human genome was sequenced, the term" epigenetics" is increasingly being
associated with the hope that we are more than just the sum of our genes. Might what we …

Recent evidence sheds light on the peculiar type of plant intelligence. Plants have
developed complex molecular networks that allow them to remember, choose, and make …

The methylome is subject to genetic and environmental effects. Their impact may depend on
sex and age, resulting in sex-and age-related physiological variation and disease …

The widely-cited model of maintenance of DNA methylation at CpG sites implies that DNA
methylation is introduced by the Dnmt3 de novo DNA methyltransferases during early …

Over the past decade, advances in both molecular developmental biology and evolutionary
ecology have made possible a new understanding of organisms as dynamic systems …

Polyploidy, or whole genome multiplication, is ubiquitous among angiosperms. Many crop
species are relatively recent allopolyploids, resulting from interspecific hybridization and …