Paternal low-dose benzo (a) pyrene exposure in rats impairs sexual development and fertility of the paternal lineage in F2 generation: A transgenerational study

BC Jorge, J Stein, ACC Reis, JN Bueno… - Toxicology, 2023 - Elsevier
Abstract The field of Paternal Origins of Health and Disease (POHaD) is highly relevant but
remains under-explored. The F2 generation from males indirectly exposed (F1-via germ …

Effect of methylphenidate on the onset of puberty and reproductive organ development in rats

F Khoubbieh, CS Erdogan, T Onel, E Yildirim… - Physiology & …, 2023 - Elsevier
Methylphenidate (MPH) is the first-line therapy for attention deficit hyperactivity disorder
(ADHD) in children and adolescents. The aim of this study was to investigate the effects …

Effect of paracetamol treatment on maternal care and reproductive outcomes in female rat offspring

JF Aleixo, MRF Pereira, BG Montagnini… - Reproduction …, 2021 - CSIRO Publishing
Paracetamol (PAR) is one of the most commonly used drugs by pregnant women because it
is considered safe for the mother and fetus. However, PAR is transferred into breast milk and …

[HTML][HTML] Impaired reproduction after exposure to ADHD drugs: Systematic review of animal studies

PB Danborg, AL Simonsen… - International Journal of …, 2017 - content.iospress.com
BACKGROUND: Few studies have reported on long-term harms caused by ADHD drugs but
they are known to impair growth. OBJECTIVE: To assess whether ADHD drugs impair …

Sulfasalazine exposure during pregnancy and lactation induces alterations in reproductive behavior in adult female rat offspring

S Forcato, AB de Oliveira Aquino… - Life Sciences, 2022 - Elsevier
Aims Sulfasalazine (SAS) is the first line drug in the treatment of chronic inflammatory bowel
diseases in pregnant women. SAS and its metabolites cross the placenta and can be …

Insights from the maternal lineage of the F2 generation after exposure to an environmentally relevant dose of benzo (a) pyrene in the male rats of F0 generation

BC Jorge, J Stein, ACC Reis… - … Science and Pollution …, 2023 - Springer
Abstract Benzo (a) pyrene (BaP) is a substance with the potential to induce endocrine
disruption in the F0 generation and cause adverse multigenerational effects (F1 generation) …

Potential disturbance of methylphenidate of gonadal hormones or pubescent development in patients with attention-deficit/hyperactivity disorder: a twelve-month …

LJ Wang, YH Huang, WJ Chou, SY Lee, CS Tsai… - Progress in Neuro …, 2021 - Elsevier
Several animal or case reports have demonstrated that methylphenidate (MPH) disrupts
endogenous gonadal hormones and interferes with the pubescent development of children …

Influência da exposição in utero a ondansetrona: possíveis efeitos teratogênicos e repercussão tardia em parâmetros reprodutivos e comportamentais em ratos …

ACC Reis - 2022 - repositorio.unesp.br
A ondansetrona é um antagonista altamente seletivo do receptor de serotonina 5HT3,
utilizado na prevenção e tratamento de náuseas e vômitos. É considerada uma droga de …

Acetaminophen affects female fertility-evidence by electron and light microscopic study

MM Hassan, RH Shaker, MH El-Kafrawy… - The Egyptian Journal …, 2020 - journals.ekb.eg
Background and aim of the work: Acetaminophen is considered the most popular used over-
the-counter (OTC) pain killer taken during pregnancy. Because of the scanty information …

[HTML][HTML] Efeito da semente de linhaça no desenvolvimento do nervo óptico na prole de ratas Wistar: análise ultraestrutural

Q Lenzi - 2017 - bdtd.ibict.br
Este estudo é de grande importância, visto o uso cada vez mais frequente de linhaça pela
população brasileira em geral, e principalmente por mulheres em idade reprodutiva …