Nucleic acid tests for clinical translation
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …
natural biopolymers composed of nucleotides that store, transmit, and express genetic …
Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
An AIE photosensitizer with simultaneous type I and type II ROS generation: efficient bacterial elimination and hypoxic tumor ablation
Y Wang, J Liao, Y Lyu, Q Guo, Z Zhu… - Advanced Functional …, 2023 - Wiley Online Library
Aggregation induced emission (AIE) photosensitizers have attracted great attention due to
their good performance in photodynamic therapy (PDT). However, the therapeutic effect of …
their good performance in photodynamic therapy (PDT). However, the therapeutic effect of …
Advances in targeting the folate receptor in the treatment/imaging of cancers
M Fernández, F Javaid, V Chudasama - Chemical science, 2018 - pubs.rsc.org
The folate receptor (FR) is a recognised biomarker for tumour cells due to its overexpression
on a large number of tumours. Consequently, the FR has been exploited by many diagnostic …
on a large number of tumours. Consequently, the FR has been exploited by many diagnostic …
An Activatable Near‐Infrared Afterglow Theranostic Prodrug with Self‐Sustainable Magnification Effect of Immunogenic Cell Death
Herein, we report an activatable near‐infrared (NIR) afterglow theranostic prodrug that
circumvents high background noise interference caused by external light excitation. The …
circumvents high background noise interference caused by external light excitation. The …
Theranostic fluorescent probes
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …
Recent progress on molecularly near-infrared fluorescent probes for chemotherapy and phototherapy
C Yan, Y Zhang, Z Guo - Coordination Chemistry Reviews, 2021 - Elsevier
Recently, molecularly fluorophores for nanotheranostics, bridging in vivo imaging and
therapeutic capability within unimolecular system, has attracted increasing attention …
therapeutic capability within unimolecular system, has attracted increasing attention …
Macrotheranostic probe with disease‐activated near‐infrared fluorescence, photoacoustic, and photothermal signals for imaging‐guided therapy
Theranostics provides opportunities for precision cancer therapy. However, theranostic
probes that simultaneously turn on their diagnostic signal and pharmacological action only …
probes that simultaneously turn on their diagnostic signal and pharmacological action only …
Enzyme‐Engineered Conjugated Polymer Nanoplatform for Activatable Companion Diagnostics and Multistage Augmented Synergistic Therapy
J Wu, Y Zhang, K Jiang, X Wang, NT Blum… - Advanced …, 2022 - Wiley Online Library
Companion diagnostics (CDx) provides critical information for precision medicine. However,
current CDx is mostly limited to in vitro tests, which cannot accurately evaluate the disease …
current CDx is mostly limited to in vitro tests, which cannot accurately evaluate the disease …
Real-time tracking and in vivo visualization of β-galactosidase activity in colorectal tumor with a ratiometric near-infrared fluorescent probe
Development of “smart” noninvasive bioimaging probes for trapping specific enzyme
activities is highly desirable for cancer therapy in vivo. Given that β-galactosidase (β-gal) is …
activities is highly desirable for cancer therapy in vivo. Given that β-galactosidase (β-gal) is …