Despite the apparent public health concern about Bovine tuberculosis (BTB) in Tanzania,
little has been done regarding the zoonotic importance of the disease and raising …

Bovine tuberculosis (bTB) is caused by Mycobacterium bovis. The incidence of bTB is
increasing in cattle herds of developed countries that have a wild life reservoir of M. bovis …

Abstract Development of a subunit vaccine for Mycobacterium tuberculosis (Mtb) depends
on the identification of Ags that induce appropriate T cell responses. Using bioinformatics …

Bordetella pertussis adenylate cyclase (CyaA) toxoid is a powerful nonreplicative
immunization vector targeting dendritic cells, which has already been used successfully in …

Bovine tuberculosis (bTb) remains a major and economically important disease of livestock.
Improved ante-mortem diagnostic tools would help to underpin novel control strategies. The …

Background. Human immunodeficiency virus (HIV)-associated tuberculosis is a major cause
of mortality in Africa. The assay of T cell interferon-γ released in response to antigens of …

The protective efficacy of four recombinant antigens (85A, 85B, superoxide dismutase [SOD],
and a fusion polypeptide [Map74F]) of Mycobacterium avium subsp. paratuberculosis (MAP) …

The attempts to find an effective antituberculous subunit vaccine are based on the
assumption that it must drive a Th1 response. In the absence of effective correlates of …

Background In the present study, we applied microarray technology to define biosignatures
by microarray transcriptome analysis in lung and spleen samples after BCG vaccination and …

Even after decades searching for a new and more effective vaccine against tuberculosis, the
scientific community is still pursuing this goal due to the complexity of its causative agent …