Alveolar-pleural fistulas causing persistent air leaks (PALs) are associated with prolonged
hospital stays and high morbidity. Prior guidelines recommend surgical repair as the gold …

OBJECTIVE: I conducted a systematic review of the use of propensity score matching in the
cardiovascular surgery literature. I examined the adequacy of reporting and whether …

Rationale: Single-center randomized controlled trials of the Zephyr endobronchial valve
(EBV) treatment have demonstrated benefit in severe heterogeneous emphysema. This is …

Rationale: This is the first multicenter randomized controlled trial to evaluate the
effectiveness and safety of Zephyr Endobronchial Valve (EBV) in patients with little to no …

Background Lung volume reduction of emphysematous lobes results in clinical improvement
for patients with severe emphysema. However, some segments within a lobe are often …

Substantial information regarding the role of lung volume reduction surgery (LVRS) in
severe emphysema emanates from the National Emphysema Treatment Trial (NETT). The …

Background: Lung volume reduction aims to improve symptoms by reducing hyperinflation.
Endoscopic approaches so far have generally been hampered in their efficacy by collateral …

The incidence of any kind of air leaks after lung resections is reportedly around 50% of
patients. The majority of these leaks doesn't require any specific intervention and ceases …

BACKGROUND: The objective of this study was to better characterize prolonged air leak
(PAL), defined as an air leak longer than 7 days, and to develop and validate a predictive …

COPD is a highly prevalent, chronic and irreversible obstructive airway disease without
curative treatment. Standard therapeutic strategies, both non-pharmacological and …