Compelling evidence supports a tight link between oxidative stress and protein aggregation
processes, which are noticeably involved in the development of proteinopathies, such as …

Autophagy is a mechanism that enables cells to maintain cellular homeostasis by removing
damaged materials and mobilizing energy reserves in conditions of starvation. Although …

The reduced form of nicotinamide adenine dinucleotide phosphate (NADPH) protects
against redox stress by providing reducing equivalents to antioxidants such as glutathione …

Response and adaptation to stress are critical for the survival of all living organisms. The
regulation of the transcriptional machinery is an important aspect of these complex …

Background Emerging evidence indicates that impaired mitophagy-mediated clearance of
defective mitochondria is a critical event in Alzheimer's disease (AD) pathogenesis. Amyloid …

Mitochondria are key regulators of cell fate through controlling ATP generation and
releasing pro-apoptotic factors. Cardiac ischemia/reperfusion (I/R) injury to the coronary …

Au nanozymes are extensively researched for their photothermal effect and catalytic
performance, but overcoming the inherent defects of poor dispersibility and thermal stability …

Mitochondria are critical for providing energy to maintain cell viability. Oxidative
phosphorylation involves the transfer of electrons from energy substrates to oxygen to …

Aims This study aimed to investigate the characteristics and mechanism of autophagy on
podocyte apoptosis under high glucose (HG) conditions and further explore the effect of …

Mammalian TFEB and TFE3, as well as their ortholog in Caenorhabditis elegans HLH‐30,
play an important role in mediating cellular response to a variety of stress conditions …