Improved mobility with metformin in patients with myotonic dystrophy type 1: a randomized controlled trial

G Bassez, E Audureau, JY Hogrel, R Arrouasse… - Brain, 2018 - academic.oup.com
Metformin, the well-known anti-diabetic drug, has been shown recently to improve the grip
test performance of the DMSXL mouse model of myotonic dystrophy type 1. The drug may …

Role of glycogen in cardiac metabolic stress

KF Xiang, J Wan, P Wang, X Liu - Metabolism, 2024 - Elsevier
Metabolic stress in the myocardium arises from a diverse array of acute and chronic
pathophysiological contexts. Glycogen mishandling is a key feature of metabolic stress …

Influence of sodium glucose cotransporter 2 inhibition on physiological adaptation to endurance exercise training

AA Newman, NC Grimm, JR Wilburn… - The Journal of …, 2019 - academic.oup.com
Context The combination of two beneficial antidiabetes interventions, regular exercise and
pharmaceuticals, is intuitively appealing. However, metformin, the most commonly …

Pioglitazone does not enhance exogenous glucose oxidation or metabolic clearance rate during aerobic exercise in men under acute high-altitude exposure

LM Margolis, MA Wilson, DJ Drummer… - American Journal …, 2024 - journals.physiology.org
Insulin insensitivity decreases exogenous glucose oxidation and metabolic clearance rate
(MCR) during aerobic exercise in unacclimatized lowlanders at high altitude (HA). Whether …

Exposure to high altitude promotes loss of muscle mass that is not rescued by metformin

ZS Fullerton, BD McNair, NA Marcello… - … Altitude Medicine & …, 2022 - liebertpub.com
Fullerton, Zackery S., Benjamin D. McNair, Nicholas A. Marcello, Emily E. Schmitt, and
Danielle R. Bruns. Exposure to high altitude promotes loss of muscle mass that is not …

UIAA Medical Commission recommendations for mountaineers, hillwalkers, trekkers, and rock and ice climbers with diabetes

D Hillebrandt, A Gurtoo, T Kupper… - … Altitude Medicine & …, 2023 - liebertpub.com
Hillebrandt, David, Anil Gurtoo, Thomas Kupper, Paul Richards, Volker Schöffl, Pankaj
Shah, Rianne van der Spek, Nikki Wallis, and Jim Milledge. UIAA Medical Commission …

Effects of long-term metformin administration associated with high-intensity interval training on physical performance, glycogen concentration, GLUT-4 content, and …

VJ Bastos-Silva, H Spineli, JC Guimarães… - Brazilian Journal of …, 2024 - SciELO Brasil
The aim was to investigate the long-term effects of metformin ingestion on high-intensity
interval training on performance, glycogen concentration (GC), GLUT-4 content, and …

Metformin anticipates peak of lactate during high-intensity interval training but no changes performance or neuromuscular response in amateur swimmers

MS Norberto, TB De Arruda, JA Cursiol… - Clinical Nutrition …, 2021 - Elsevier
Background & aims Metformin demonstrated potential to improve metabolic efficiency in
short-intense and prolonged-continuous efforts. The present study investigates the acute …

Acute metformin administration increases mean power and the early Power phase during a Wingate test in healthy male subjects

VJ Bastos-Silva, AH Marinho… - European Journal of …, 2022 - Taylor & Francis
The present study tested the hypothesis that acute metformin would increase peak power
measured during a Wingate test. Fourteen men (24±6 years; 75.8±10.2 kg; 177±7 cm) …

Antidiabéticos eo uso off-label para aumento do desempenho esportivo: uma revisão narrativa

WS Silva - 2024 - lume.ufrgs.br
Introdução: A automedicação é um fenômeno preocupante para as agências regulatórias
em todo o mundo, sendo considerada como uma forma de uso irracional de medicamentos …