Potential contributions of antioxidants to cancer therapy: immunomodulation and radiosensitization

A Thyagarajan, RP Sahu - Integrative cancer therapies, 2018 - journals.sagepub.com
Antioxidants play important roles in the maintenance of cellular integrity and thus are critical
in maintaining the homeostasis of the host immune system. A balance between the levels of …

Curcumin analogues and derivatives with anti-proliferative and anti-inflammatory activity: Structural characteristics and molecular targets

E Chainoglou, D Hadjipavlou-Litina - Expert opinion on drug …, 2019 - Taylor & Francis
ABSTRACT Introduction: Curcumin (Diferuloylmethane) is a natural phenolic compound,
which belongs to the curcuminoid family, presenting pleiotropic activity and low …

The formulation and delivery of curcumin with solid lipid nanoparticles for the treatment of on non-small cell lung cancer both in vitro and in vivo

P Wang, L Zhang, H Peng, Y Li, J Xiong, Z Xu - Materials Science and …, 2013 - Elsevier
Curcumin was determined to have anticancer potency on several kinds of carcinoma.
However, its medical application was limited because of its poor bioavailability, unsatisfying …

Nanocurcumin: preparation, characterization and cytotoxic effects towards human laryngeal cancer cells

DH Hanna, GR Saad - RSC advances, 2020 - pubs.rsc.org
The aim of the present study was to prepare curcumin nanoparticles (nanocurcumin) by a
sol-oil method to improve curcumin absorption and bioavailability, and to investigate the …

Curcumin induces apoptosis in gallbladder carcinoma cell line GBC-SD cells

TY Liu, ZJ Tan, L Jiang, JF Gu, XS Wu, Y Cao… - Cancer cell …, 2013 - Springer
Background Gallbladder carcinoma is a malignant tumor with a very low 5-year survival rate
because of the difficulty with its early diagnosis and the very poor prognosis of the advanced …

Synthesis, in vitro, in silico and DFT studies of indole curcumin derivatives as potential anticancer agents

A Parthiban, R Sivasankar, B Rajdev, RN Asha… - Journal of Molecular …, 2022 - Elsevier
The curcumin derivatives were synthesized for the first time using simple starting materials
through a three-component reaction, yielding high purity compounds. The synthesized …

Evaluation of High-Performance Curcumin Nanocrystals for Pulmonary Drug Delivery Both In Vitro and In Vivo

L Hu, D Kong, Q Hu, N Gao, S Pang - Nanoscale research letters, 2015 - Springer
This paper focused on formulating high-performance curcumin spray-dried powders for
inhalation (curcumin-DPIs) to achieve a high lung concentration. Curcumin-DPIs were …

MACC1-dependent antitumor effect of curcumin in colorectal cancer

N Güllü, J Smith, P Herrmann, U Stein - Nutrients, 2022 - mdpi.com
Metastasis is the main reason for the high mortality rate of colorectal cancer (CRC) patients.
Despite the whole improvement in the field of cancer medicine, the treatment options for the …

Virtual screening of curcumin and its analogs against the spike surface glycoprotein of SARS-CoV-2 and SARS-CoV

A Patel, M Rajendran, A Shah, H Patel… - Journal of …, 2022 - Taylor & Francis
COVID-19, a new pandemic caused by SARS-CoV-2, was first identified in 2019 in Wuhan,
China. The novel corona virus SARS-CoV-2 and the 2002 SARS-CoV have 74% identity …

Synthetic curcumin analog: Inhibiting the invasion, angiogenesis, and metastasis in human laryngeal carcinoma cells via NF-kB pathway

K Mohankumar, AP Francis, S Pajaniradje… - Molecular Biology …, 2021 - Springer
Background Laryngeal carcinoma, the most common among head and neck squamous cell
carcinoma (HNSCC), induces 1% of all cancer deaths. Curcumin the active constituent of …