Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …

Intrarenal autoregulatory mechanisms maintain renal blood flow (RBF) and glomerular
filtration rate (GFR) independent of renal perfusion pressure (RPP) over a defined range (80 …

Abstract Small arterioles (40–150 μm) contribute to the majority of vascular resistance within
organs and tissues. Under resting conditions, the basal tone of these vessels is determined …

The endothelium controls vascular tone not only by releasing nitric oxide (NO) and
prostacyclin but also by other pathways causing hyperpolarization of the underlying smooth …

Endothelial cells in resistance arteries, arterioles, and capillaries express a diverse array of
ion channels that contribute to Cell-Cell communication in the microcirculation. Endothelial …

This review is concerned with understanding how vasodilation initiated from local sites in the
tissue can spread to encompass multiple branches of the resistance vasculature. Within …

Rationale: The coordination of vascular smooth muscle cell constriction plays an important
role in vascular function, such as regulation of blood pressure; however, the mechanism …

VSMC s in resistance arteries and arterioles express a diverse array of KV channels with
members of the KV 1, KV 2 and KV 7 families being particularly important. Members of the …

Potassium channels importantly contribute to the regulation of vascular smooth muscle
(VSM) contraction and growth. They are the dominant ion conductance of the VSM cell …

The endothelium plays a key role in the control of vascular tone and alteration in endothelial
cell function contributes to several cardiovascular disease states. Endothelium-dependent …