A guide to plasma membrane solute carrier proteins

MD Pizzagalli, A Bensimon… - The FEBS …, 2021 - Wiley Online Library
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily
of transporter proteins and their roles in human cells. The SLC superfamily currently …

[PDF][PDF] Manganese metabolism in humans

P Chen, J Bornhorst, MA Aschner - 2018 - publishup.uni-potsdam.de
Manganese (Mn) is an essential nutrient for intracellular activities; it functions as a cofactor
for a variety of enzymes, including arginase, glutamine synthetase (GS), pyruvate …

Metalloimmunology: The metal ion-controlled immunity

C Wang, R Zhang, X Wei, M Lv, Z Jiang - Advances in immunology, 2020 - Elsevier
Metals are essential components in all forms of life required for the function of nearly half of
all enzymes and are critically involved in virtually all fundamental biological processes …

Clinical and molecular aspects of lead toxicity: An update

P Mitra, S Sharma, P Purohit… - Critical reviews in clinical …, 2017 - Taylor & Francis
Lead toxicity is a major public health issue in developed and developing countries. Both
acute and chronic lead exposure has the potential to cause many deleterious systematic …

Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies

TV Peres, MRC Schettinger, P Chen… - BMC Pharmacology and …, 2016 - Springer
Manganese (Mn) is an essential heavy metal. However, Mn's nutritional aspects are
paralleled by its role as a neurotoxicant upon excessive exposure. In this review, we …

The role of Fe, Zn, and Cu in pregnancy

K Grzeszczak, S Kwiatkowski, D Kosik-Bogacka - Biomolecules, 2020 - mdpi.com
Iron (Fe), copper (Cu), and zinc (Zn) are microelements essential for the proper functioning
of living organisms. These elements participatein many processes, including cellular …

Molecular mechanisms and genetics of oxidative stress in Alzheimer's disease

F Cioffi, RHI Adam, K Broersen - Journal of Alzheimer's …, 2019 - content.iospress.com
Alzheimer's disease is the most common neurodegenerative disorder that can cause
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …

Manganese homeostasis in the nervous system

P Chen, S Chakraborty… - Journal of …, 2015 - Wiley Online Library
Manganese (Mn) is an essential heavy metal that is naturally found in the environment. Daily
intake through dietary sources provides the necessary amount required for several key …

Molecular mechanisms of metal toxicity in the pathogenesis of Alzheimer's disease

MT Kabir, MS Uddin, S Zaman, Y Begum… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is the most common form of dementia, which is progressively
affecting elderly people. The dyshomeostasis of biometals and accumulation of toxic metals …

A review of the health hazards posed by cobalt

DJ Paustenbach, BE Tvermoes, KM Unice… - Critical reviews in …, 2013 - Taylor & Francis
Cobalt (Co) is an essential element with ubiquitous dietary exposure and possible
incremental exposure due to dietary supplements, occupation and medical devices. Adverse …