[HTML][HTML] Protective effects of flavonoids against Alzheimer's disease: pathological hypothesis, potential targets, and structure–activity relationship

J Li, M Sun, X Cui, C Li - International Journal of Molecular Sciences, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease with high morbidity and mortality,
for which there is no available cure. Currently, it is generally believed that AD is a disease …

[HTML][HTML] Cognitive function and consumption of fruit and vegetable polyphenols in a young population: Is there a relationship?

JÁ Carrillo, MP Zafrilla, J Marhuenda - Foods, 2019 - mdpi.com
Scientific evidence has shown the relationship between consumption of fruits and
vegetables and their polyphenols with the prevention or treatment of diseases. The aim of …

[HTML][HTML] Acai Berry (Euterpe sp.) Extracts Are Neuroprotective against L-Glutamate-Induced Toxicity by Limiting Mitochondrial Dysfunction and Cellular Redox Stress

MN ALNasser, AM AlSaadi, A Whitby, DH Kim… - Life, 2023 - mdpi.com
Aberrant accumulation of the neurotransmitter L-glutamate (L-Glu) has been implicated as a
mechanism of neurodegeneration, and the release of L-Glu after stroke onset leads to a …

[PDF][PDF] Correlation between total phenols content, antioxidant power and cytotoxicity

MA Osman, GI Mahmoud… - Biointerface Res. Appl …, 2020 - researchgate.net
Plants are commonly used in traditional medicines against diseases according to their
cytotoxic effect. Therefore, studying the relationship between antioxidant activity and …

[HTML][HTML] Amburana cearensis: Pharmacological and Neuroprotective Effects of Its Compounds

JHC Silva, RS Ferreira, EP Pereira, S Braga-de-Souza… - Molecules, 2020 - mdpi.com
Amburana cearensis AC Smith is an endemic tree from Northeastern Brazil used in folk
medicine as teas, decocts and syrups for the treatment of various respiratory and …

Oxidized quercetin has stronger anti-amyloid activity and anti-aging effect than native form

J Li, J Wang, Z Huang, X Cui, C Li - … and Physiology Part C: Toxicology & …, 2023 - Elsevier
Quercetin (QUE) is one of the most widely distributed and used flavonoid. It has many
biological activities and pharmacological effect. As a polyhydroxy phenol, QUE is easily …

Pongamol Prevents Neurotoxicity via the Activation of MAPKs/Nrf2 Signaling Pathway in H2O2-Induced Neuronal PC12 Cells and Prolongs the Lifespan of …

S Wu, J Miao, S Zhu, X Wu, J Shi, J Zhou, Y Xing… - Molecular …, 2024 - Springer
Despite tremendous advances in modern medicine, effective prevention or therapeutic
strategies for age-related neurodegenerative diseases such as Alzheimer's disease (AD) …

Investigation of therapeutic effect of curcumin α and β glucoside anomers against Alzheimer's disease by the nose to brain drug delivery

N Ahmadi, MJ Hosseini, K Rostamizadeh, M Anoush - Brain Research, 2021 - Elsevier
Alzheimer's disease (AD) is one of the greatest geriatric medicinal challenges of our century
and is the main disease leading to dementia. Despite extensive scientific research …

[HTML][HTML] Systematic Analysis of Combined Antioxidant and Membrane-Stabilizing Properties of Several Lamiaceae Family Kazakhstani Plants for Potential Production …

A Ydyrys, N Zhaparkulova, A Aralbaeva, A Mamataeva… - Plants, 2021 - mdpi.com
One of the most important compounds that exhibit a wide range of biological activities with
especially strong antioxidant action are plant polyphenols. In the course of the experiment …

[HTML][HTML] Renoprotective and oxidative stress-modulating effects of taxifolin against cadmium-induced nephrotoxicity in mice

AI Algefare - Life, 2022 - mdpi.com
Cadmium (Cd) is an inessential trace metal that accumulates in the kidney and may lead to
renal toxicity by mediating oxidative stress (OS), inflammatory reactions, and apoptosis. The …