Ca2+ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract
The gastrointestinal (GI) tract displays multiple motor patterns that move nutrients and
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …
wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI …
Possible beneficial actions of caffeine in SARS-CoV-2
BS Romero-Martinez, LM Montano… - International Journal of …, 2021 - mdpi.com
The COVID-19 pandemic has established an unparalleled necessity to rapidly find effective
treatments for the illness; unfortunately, no specific treatment has been found yet. As this is a …
treatments for the illness; unfortunately, no specific treatment has been found yet. As this is a …
Inhibitors of L-type calcium channels show therapeutic potential for treating SARS-CoV-2 infections by preventing virus entry and spread
COVID-19 is caused by a novel coronavirus, the severe acute respiratory syndrome
coronavirus (CoV)-2 (SARS-CoV-2). The virus is responsible for an ongoing pandemic and …
coronavirus (CoV)-2 (SARS-CoV-2). The virus is responsible for an ongoing pandemic and …
FDA approved calcium channel blockers inhibit SARS-CoV-2 infectivity in epithelial lung cells
COVID-19 has infected more than 41 million people worldwide with over 1.1 million deaths
and is caused by the severe acute respiratory syndrome coronavirus (CoV) 2 (SARS-CoV …
and is caused by the severe acute respiratory syndrome coronavirus (CoV) 2 (SARS-CoV …
Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation
NA Rivero-Segura, E Flores-Soto… - PloS one, 2017 - journals.plos.org
Prolactin (PRL) is a peptidic hormone that displays pleiotropic functions in the organism
including different actions in the brain. PRL exerts a neuroprotective effect against …
including different actions in the brain. PRL exerts a neuroprotective effect against …
Could lower testosterone in older men explain higher COVID-19 morbidity and mortalities?
LM Montano, B Sommer, H Solis-Chagoyan… - International Journal of …, 2022 - mdpi.com
The health scourge imposed on humanity by the COVID-19 pandemic seems not to recede.
This fact warrants refined and novel ideas analyzing different aspects of the illness. One …
This fact warrants refined and novel ideas analyzing different aspects of the illness. One …
Store‐operated calcium entry is required for sustained contraction and Ca2+ oscillations of airway smooth muscle
J Chen, MJ Sanderson - The Journal of physiology, 2017 - Wiley Online Library
Key points Airway hyper‐responsiveness in asthma is driven by excessive contraction of
airway smooth muscle cells (ASMCs). Agonist‐induced Ca2+ oscillations underlie this …
airway smooth muscle cells (ASMCs). Agonist‐induced Ca2+ oscillations underlie this …
Estrogen receptors differentially regulate intracellular calcium handling in human nonasthmatic and asthmatic airway smooth muscle cells
S Bhallamudi, J Connell, CM Pabelick… - … of Physiology-Lung …, 2020 - journals.physiology.org
Asthma is defined as chronic inflammation of the airways and is characterized by airway
remodeling, hyperresponsiveness, and acute bronchoconstriction of airway smooth muscle …
remodeling, hyperresponsiveness, and acute bronchoconstriction of airway smooth muscle …
Acute cigarette smoke or extract exposure rapidly activates TRPA1-mediated calcium influx in primary human airway smooth muscle cells
Tobacco smoking is the largest risk factor for developing chronic obstructive pulmonary
disease (COPD), and is associated with hyperresponsiveness of airway smooth muscle …
disease (COPD), and is associated with hyperresponsiveness of airway smooth muscle …
Estrogenic modulation of ionic channels, pumps and exchangers in Airway smooth muscle
BS Romero-Martínez, B Sommer… - International Journal of …, 2023 - mdpi.com
To preserve ionic homeostasis (primarily Ca2+, K+, Na+, and Cl−), in the airway smooth
muscle (ASM) numerous transporters (channels, exchangers, and pumps) regulate the influx …
muscle (ASM) numerous transporters (channels, exchangers, and pumps) regulate the influx …