Free radical scavenging, antibacterial potentials and spectroscopic characterizations of benzoyl thiourea derivatives and their metal complexes
In this work, two series of benzoyl thiourea derivatives (TH01-TH05),(TH06-TH10) and their
metal complexes were successfully synthesized in good yields (up to 90%) using efficient …
metal complexes were successfully synthesized in good yields (up to 90%) using efficient …
Synthesis and Biological Importance of 2-(thio) ureabenzothiazoles
MC Rosales-Hernández, JE Mendieta-Wejebe… - Molecules, 2022 - mdpi.com
The (thio) urea and benzothiazole (BT) derivatives have been shown to have a broad
spectrum of biological activities. These groups, when bonded, result in the 2-(thio) …
spectrum of biological activities. These groups, when bonded, result in the 2-(thio) …
Synthesis of isoniazid analogs with promising antituberculosis activity and bioavailability: biological evaluation and computational studies
R Gavadia, J Rasgania, MV Basil, V Chauhan… - Journal of Molecular …, 2023 - Elsevier
A series of aliphatic isoniazid carbo (x/thio) amides has been synthesized by a facile one-pot
green method in aqueous media by harnessing microwave irradiations. In vitro …
green method in aqueous media by harnessing microwave irradiations. In vitro …
Facile synthesis, pharmacological and In silico analysis of succinimide derivatives: An approach towards drug discovery
J Rasgania, R Gavadia, K Jakhar - Journal of Molecular Structure, 2023 - Elsevier
The hybrid heterocyclic scaffolds possess extensive medicinal values and significant
pharmaceutical usage. A series of N-substituted-2, 5-dioxopyrrolidine carboxamides …
pharmaceutical usage. A series of N-substituted-2, 5-dioxopyrrolidine carboxamides …
Synthesis of Novel N-Methylmorpholine-Substituted Benzimidazolium Salts as Potential α-Glucosidase Inhibitors
The α-glucosidase enzyme, located in the brush border of the small intestine, is responsible
for overall glycemic control in the body. It hydrolyses the 1, 4-linkage in the carbohydrates to …
for overall glycemic control in the body. It hydrolyses the 1, 4-linkage in the carbohydrates to …
Contribution to the Synthesis, Characterization, Separation and Quantification of New N-Acyl Thiourea Derivatives with Antimicrobial and Antioxidant Potential
The present study aimed to synthesize, characterize, and validate a separation and
quantification method of new N-acyl thiourea derivatives (1a–1o), incorporating thiazole or …
quantification method of new N-acyl thiourea derivatives (1a–1o), incorporating thiazole or …
Synthesis, analgesic, anti-inflammatory, COX/5-LOX inhibition, ulcerogenic evaluation, and docking study of benzimidazole bearing indole and benzophenone …
KMJ Nagesh, T Prashanth, HA Khamees… - Journal of Molecular …, 2022 - Elsevier
Inflammation therapy is particularly focused on the development of safer non-steroidal anti-
inflammatory drugs (NSAIDs), administered to control inflammation. It is typically considered …
inflammatory drugs (NSAIDs), administered to control inflammation. It is typically considered …
N-substitution reactions of 2-aminobenzimidazoles to access pharmacophores
II Padilla-Martínez, A Cruz… - Current Organic …, 2023 - ingentaconnect.com
Benzimidazole (BI) and its derivatives are interesting molecules in medicinal chemistry
because several of these compounds have a diversity of biological activities and some of …
because several of these compounds have a diversity of biological activities and some of …
Synthesis and antitumor evaluation of menthone-derived pyrimidine-urea compounds as potential PI3K/Akt/mTOR signaling pathway inhibitor
M Huang, W Duan, N Chen, G Lin, X Wang - Frontiers in Chemistry, 2022 - frontiersin.org
A series of novel menthone derivatives bearing pyrimidine and urea moieties was designed
and synthesized to explore more potent natural product-derived antitumor agents. The …
and synthesized to explore more potent natural product-derived antitumor agents. The …
Synthesis of thiazole-based-thiourea analogs: as anticancer, antiglycation and antioxidant agents, structure activity relationship analysis and docking study
This work reports the convenient approach for the synthesis of thiazole based thiourea
derivatives (1-21) from 2-bromo-1-(4-fluorophenyl) thiazole-1-one and phenyl …
derivatives (1-21) from 2-bromo-1-(4-fluorophenyl) thiazole-1-one and phenyl …