Osteosarcoma is the most common primary malignant tumour of the bone. Osteosarcoma
incidence is bimodal, peaking at 18 and 60 years of age, and is slightly more common in …

Sarcomas account for over 20% of all pediatric solid malignant cancers and less than 1% of
all adult solid malignant cancers. The vast majority of diagnosed sarcomas will be soft tissue …

Background Estimation of the risk of adverse long‐term outcomes such as second malignant
neoplasms and infertility often requires reproducible quantification of exposures. The …

Background The occurrence of subsequent neoplasms has direct impact on the quantity and
quality of life in cancer survivors. We have expanded our analysis of these events in the …

Despite significant advancements in the diagnosis and treatment of osteosarcoma to date,
overall survival has remained relatively constant for over 2 decades. The challenge in …

Purpose Childhood cancer survivors (CCSs) are at increased risk for subsequent malignant
neoplasms (SMNs). We evaluated the long-term risk of SMNs in a well-characterized cohort …

Background The proportion of pediatric and adolescent cancer patients surviving 5 years
has increased during the past four decades. This growing population of survivors remains at …

Background Previous studies have shown decreased pregnancy rates and early
menopause in female cancer survivors; however, infertility rates and reproductive …

Background The late effects of bone marrow transplantation, including cancer, need to be
determined in a large population at risk. Methods We studied 19,229 patients who received …

PURPOSE: Survivors of childhood and adolescent cancer are at risk for long-term effects of
disease and treatment. The Childhood Cancer Survivor Study assessed overall and cause …