Nerve growth factor (NGF) antagonism is on the verge of becoming a powerful analgesic
treatment for numerous conditions, including osteoarthritis and lower back pain. This review …

Chronic pain caused by injury or disease of the nervous system (neuropathic pain) has been
linked to persistent electrical hyperactivity of the sensory neurons (nociceptors) specialized …

Nociception, the sensory mechanism that allows animals to sense and avoid potentially
tissue-damaging stimuli, is critical for survival. This process relies on nociceptors, which are …

The simple tripartite classification of sensory neurons as A-beta, A-delta, and C fibers fails to
convey the complexity of the neurons that encode stimuli as diverse as the texture of a …

Noxious substances, called algogens, cause pain and are used as defensive weapons by
plants and stinging insects. We identified four previously unknown instances of algogen …

Naked mole rats (NMRs) are renowned for their exceptional longevity and remarkable
maintenance of health throughout their lifetime. Their subterranean lifestyle has led to …

Nerve growth factor (NGF) injected into the human skin causes local hyperalgesia to
mechanical and electrical stimuli lasting for weeks. Pig data suggested axonal sensitization …

Acid-sensing ion channels (ASICs) are a family of ion channels comprised of six subunits
encoded by four genes and they are expressed throughout the peripheral and central …

Opportunities for new insight into aging from the naked mole-rat and other non-traditional models
| Nature Aging Skip to main content Thank you for visiting nature.com. You are using a browser …

Ethnopharmacological relevance Galangin, a bioactive compound extracted from Alpinia
officinarum Hance (Zingiberaceae), a plant with significant ethnopharmacological …