The immunopathogenesis of narcolepsy type 1
Abstract Narcolepsy type 1 (NT1) is a chronic sleep disorder resulting from the loss of a
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …
[HTML][HTML] Sleep disorders during pregnancy: an underestimated risk factor for gestational diabetes mellitus
D Eleftheriou, KI Athanasiadou, E Sifnaios, E Vagiakis… - Endocrine, 2024 - Springer
Sleep disorders are highly prevalent during pregnancy and significantly affect women's
health and quality of life. Gestational diabetes mellitus (GDM) is one of the most common …
health and quality of life. Gestational diabetes mellitus (GDM) is one of the most common …
Autoimmunity and SARS‐CoV‐2 infection: Unraveling the link in neurological disorders
D Latorre - European Journal of Immunology, 2022 - Wiley Online Library
Abstract According to the World Health Organization, severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) has already infected more than 400 million people and …
coronavirus 2 (SARS‐CoV‐2) has already infected more than 400 million people and …
Connecting the dots: An updated review of the role of autoimmunity in narcolepsy and emerging immunotherapeutic approaches
Abstract Background Narcolepsy type 1 (NT1) is a chronic disorder characterized by
pathological daytime sleepiness and cataplexy due to the disappearance of orexin …
pathological daytime sleepiness and cataplexy due to the disappearance of orexin …
Larger hypothalamic volume in narcolepsy type 1
Abstract Study Objectives Narcolepsy type 1 (NT1) is a neurological sleep disorder.
Postmortem studies have shown 75%–90% loss of the 50 000–70 000 hypocretin-producing …
Postmortem studies have shown 75%–90% loss of the 50 000–70 000 hypocretin-producing …
[HTML][HTML] Pitolisant-supported bridging during drug holidays to deal with tolerance to modafinil in patients with narcolepsy
Y Winter, C Lang, U Kallweit, D Apel, V Fleischer… - Sleep Medicine, 2023 - Elsevier
Study objectives Modafinil is a common treatment for excessive daytime sleepiness (EDS) in
narcolepsy. The long-term use of modafinil can lead to tolerance with the loss of efficacy and …
narcolepsy. The long-term use of modafinil can lead to tolerance with the loss of efficacy and …
[HTML][HTML] An update on Kleine–Levin syndrome
SO Qasrawi, AS BaHammam - Current Sleep Medicine Reports, 2023 - Springer
Abstract Purpose of Review Kleine–Levin syndrome (KLS) is a rare relapsing–remitting
sleep disorder distinguished by recurrent periods of severe hypersomnia accompanied by …
sleep disorder distinguished by recurrent periods of severe hypersomnia accompanied by …
[HTML][HTML] Pharmacological Treatments of Sleep–Wake Disorders: Update 2023
MS Kallweit, NP Kallweit, U Kallweit - Clinical and Translational …, 2023 - mdpi.com
Biological, environmental, behavioral, and social factors can influence sleep and lead to
sleep disorders or diseases. Sleep disorders are common, numerous, and heterogeneous in …
sleep disorders or diseases. Sleep disorders are common, numerous, and heterogeneous in …
Diurnal changes in blood pressure and heart rate in children with narcolepsy with cataplexy
J Wang, Z Yan, X Dong, J Li, L Zhao… - Journal of Sleep …, 2023 - Wiley Online Library
The hypocretin neurons in the lateral hypothalamus are connected not only to brain
alertness systems but also to brainstem nuclei that regulate blood pressure and heart rate …
alertness systems but also to brainstem nuclei that regulate blood pressure and heart rate …
[HTML][HTML] Tetrad of Narcolepsy Type 1: Treatment and Management
K Gandhi, S Ferdous - Cureus, 2024 - ncbi.nlm.nih.gov
Narcolepsy is a chronic condition that brings about excessive daytime sleepiness. It can be
classified into two types: narcolepsy type 1 (presence of cataplexy, which is marked by …
classified into two types: narcolepsy type 1 (presence of cataplexy, which is marked by …