Mendelian randomization

E Sanderson, MM Glymour, MV Holmes… - Nature Reviews …, 2022 - nature.com
Mendelian randomization (MR) is a term that applies to the use of genetic variation to
address causal questions about how modifiable exposures influence different outcomes …

Heart disease and stroke statistics—2022 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, A Alonso… - Circulation, 2022 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

2021 ESC Guidelines on cardiovascular disease prevention in clinical practice: Developed by the Task Force for cardiovascular disease prevention in clinical practice …

FLJ Visseren, F Mach, YM Smulders… - European heart …, 2021 - academic.oup.com
Atherosclerotic cardiovascular (CV) disease (ASCVD) incidence and mortality rates are
declining in many countries in Europe, but it is still a major cause of morbidity and mortality …

American Association of Clinical Endocrinology clinical practice guideline: developing a diabetes mellitus comprehensive care plan—2022 update

L Blonde, GE Umpierrez, SS Reddy, JB McGill… - Endocrine Practice, 2022 - Elsevier
Objective The objective of this clinical practice guideline is to provide updated and new
evidence-based recommendations for the comprehensive care of persons with diabetes …

Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies—a consensus …

HN Ginsberg, CJ Packard, MJ Chapman… - European heart …, 2021 - academic.oup.com
Recent advances in human genetics, together with a large body of epidemiologic,
preclinical, and clinical trial results, provide strong support for a causal association between …

Metabolic (dysfunction)-associated fatty liver disease in individuals of normal weight

M Eslam, HB El-Serag, S Francque, SK Sarin… - Nature reviews …, 2022 - nature.com
Metabolic (dysfunction)-associated fatty liver disease (MAFLD) affects up to a third of the
global population; its burden has grown in parallel with rising rates of type 2 diabetes …

Polygenic risk scores for cardiovascular disease: a scientific statement from the American Heart Association

JW O'Sullivan, S Raghavan, C Marquez-Luna… - Circulation, 2022 - Am Heart Assoc
Cardiovascular disease is the leading contributor to years lost due to disability or premature
death among adults. Current efforts focus on risk prediction and risk factor mitigation ‚which …

[HTML][HTML] Профилактика хронических неинфекционных заболеваний в Российской Федерации. Национальное руководство 2022

ОМ Драпкина, АВ Концевая, АМ Калинина… - Кардиоваскулярная …, 2022 - cyberleninka.ru
Члены Комитета экспертов подтвердили отсутствие финансовой поддержки/конфликта
интересов. В случае сообщения о наличии конфликта интересов, член (ы) Комитета …

Metabolism of triglyceride-rich lipoproteins in health and dyslipidaemia

J Boren, MR Taskinen, E Björnson… - Nature Reviews …, 2022 - nature.com
Accumulating evidence points to the causal role of triglyceride-rich lipoproteins and their
cholesterol-enriched remnants in atherogenesis. Genetic studies in particular have not only …

High-density lipoprotein revisited: biological functions and clinical relevance

A von Eckardstein, BG Nordestgaard… - European heart …, 2023 - academic.oup.com
Previous interest in high-density lipoproteins (HDLs) focused on their possible protective
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …