[HTML][HTML] Combination antifungal therapy for cryptococcal meningitis

JN Day, TTH Chau, M Wolbers, PP Mai… - … England Journal of …, 2013 - Mass Medical Soc
Background Combination antifungal therapy (amphotericin B deoxycholate and flucytosine)
is the recommended treatment for cryptococcal meningitis but has not been shown to reduce …

[HTML][HTML] Proteomics of Cryptococcus neoformans: From the Lab to the Clinic

B Muselius, SL Durand, J Geddes-McAlister - International Journal of …, 2021 - mdpi.com
Fungal pathogens cause an array of diseases by targeting both immunocompromised and
immunocompetent hosts. Fungi overcome our current arsenal of antifungals through the …

The lysosome-phagosome pathway mediates immune regulatory mechanisms in Mesocentrotus nudus against Vibrio coralliilyticus infection

Y Wang, Q Wang, L Chen, B Li - Fish & Shellfish Immunology, 2023 - Elsevier
Sea urchins are a popular model species for studying invertebrate diseases. The immune
regulatory mechanisms of the sea urchin Mesocentrotus nudus during pathogenic infection …

[HTML][HTML] Chronic exercise remodels the lysine acetylome in the mouse hippocampus

P Qian, F Ma, W Zhang, D Cao, L Li, Z Liu… - Frontiers in Molecular …, 2022 - frontiersin.org
Physical exercise benefits hippocampal function through various molecular mechanisms.
Protein acetylation, a conserved and widespread post-translational modification, is involved …

Comparative miRNA transcriptomics of macaques and mice reveals MYOC is an inhibitor for Cryptococcus neoformans invasion into the brain

H Li, X Han, W Du, Y Meng, Y Li, T Sun… - Emerging Microbes & …, 2022 - Taylor & Francis
Cryptococcal meningoencephalitis (CM) is emerging as an infection in HIV/AIDS patients
shifted from primarily ARTnaive to ART-experienced individuals, as well as patients with …

[HTML][HTML] Pathogen-host interaction repertoire at proteome and posttranslational modification levels during fungal infections

Y Li, H Li, T Sun, C Ding - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
Prevalence of fungal diseases has increased globally in recent years, which often
associated with increased immunocompromised patients, aging populations, and the novel …

[HTML][HTML] The LysR-Type Transcriptional Regulator YeeY Plays Important Roles in the Regulatory of Furazolidone Resistance in Aeromonas hydrophila

Y Fu, L Zhang, G Wang, Y Lin, S Ramanathan… - Frontiers in …, 2020 - frontiersin.org
Aeromonas hydrophila is an aquatic pathogen of freshwater fish. The emergence of
widespread antimicrobial-resistance strains of this pathogen has caused increasing rates of …

[HTML][HTML] Rhamnolipid Enhances the Nitrogen Fixation Activity of Azotobacter chroococcum by Influencing Lysine Succinylation

J Li, H Pan, H Yang, C Wang, H Liu, H Zhou… - Frontiers in …, 2021 - frontiersin.org
The enhancement of nitrogen fixation activity of diazotrophs is essential for safe crop
production. Lysine succinylation (KSuc) is widely present in eukaryotes and prokaryotes and …

[HTML][HTML] Quantitative proteomics analysis reveals an important role of the transcriptional regulator UidR in the bacterial biofilm formation of Aeromonas hydrophila

X Li, F Tian, B Zhang, L Zhang, X Chen… - Frontiers in Cellular …, 2024 - frontiersin.org
Introduction Bacterial biofilm is a well-known characteristic that plays important roles in
diverse physiological functions, whereas the current intrinsic regulatory mechanism of its …

Global analysis of lysine acetylation in the brain cortex of K18‐hACE2 mice infected with SARS‐CoV‐2

Q Wang, W Peng, Y Yang, Y Wu, R Han, T Ding… - …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has infected hundreds of
millions of people all over the world and thus threatens human life. Clinical evidence shows …