Beyond the joints, the extra-articular manifestations in rheumatoid arthritis

A Conforti, I Di Cola, V Pavlych, P Ruscitti… - Autoimmunity …, 2021 - Elsevier
Rheumatoid arthritis (RA) is an inflammatory disease typically affecting the joints, but the
systemic inflammatory process may involve other tissues and organs. Many extra-articular …

Presentation, diagnosis and clinical course of the spectrum of progressive-fibrosing interstitial lung diseases

V Cottin, NA Hirani, DL Hotchkin… - European …, 2018 - Eur Respiratory Soc
Although these conditions are rare, a proportion of patients with interstitial lung diseases
(ILDs) may develop a progressive-fibrosing phenotype. Progressive fibrosis is associated …

Interstitial lung disease in connective tissue disorders

A Fischer, R Du Bois - The lancet, 2012 - thelancet.com
Some of the most pressing challenges associated with interstitial lung disease (ILD) are how
best to define, diagnose, and treat connective tissue disease-associated ILD (CTD-ILD) …

[HTML][HTML] Utility of KL-6/MUC1 in the clinical management of interstitial lung diseases

N Ishikawa, N Hattori, A Yokoyama, N Kohno - Respiratory investigation, 2012 - Elsevier
Interstitial lung diseases (ILDs) are a diverse group of pulmonary disorders characterized by
various patterns of inflammation and fibrosis in the interstitium of the lung. Because injury …

Idiopathic pulmonary fibrosis

TJ Gross, GW Hunninghake - New England Journal of Medicine, 2001 - Mass Medical Soc
Idiopathic pulmonary fibrosis is characterized by radiographically evident interstitial
infiltrates predominantly affecting the lung bases and by progressive dyspnea and …

Diagnosis and treatment of connective tissue disease-associated interstitial lung disease

R Vij, ME Strek - Chest, 2013 - Elsevier
Interstitial lung disease (ILD) is one of the most serious pulmonary complications associated
with connective tissue diseases (CTDs), resulting in significant morbidity and mortality …

Interstitial lung disease

KM Antoniou, GA Margaritopoulos… - European …, 2014 - Eur Respiratory Soc
Interstitial lung diseases are a group of diffuse parenchymal lung disorders associated with
substantial morbidity and mortality. Knowledge achieved in recent years has resulted in the …

Connective tissue disease-associated interstitial lung disease: a call for clarification

A Fischer, SG West, JJ Swigris, KK Brown, RM Du Bois - Chest, 2010 - Elsevier
This commentary highlights the present dilemmas surrounding the classification of a patient
with interstitial pneumonia who has clinical features suggesting an associated connective …

[HTML][HTML] Exploring efficacy and safety of oral Pirfenidone for progressive, non-IPF lung fibrosis (RELIEF)-a randomized, double-blind, placebo-controlled, parallel …

J Behr, P Neuser, A Prasse, M Kreuter, K Rabe… - BMC pulmonary …, 2017 - Springer
Background Pirfenidone is currently approved in the EU for the treatment of mild to moderate
idiopathic pulmonary fibrosis (IPF) and offers a beneficial risk-benefit profile. However, there …

Combined pulmonary fibrosis and emphysema syndrome in connective tissue disease

V Cottin, H Nunes, L Mouthon… - Arthritis & …, 2011 - Wiley Online Library
Abstract Objective Connective tissue diseases (CTDs) are associated with several interstitial
lung diseases. The aim of this study was to describe the recently individualized syndrome of …