Tranexamic acid for the prevention of postpartum hemorrhage in women undergoing cesarean delivery: an updated meta-analysis

I Bellos, V Pergialiotis - American Journal of Obstetrics and Gynecology, 2022 - Elsevier
Objective This study aimed to assess the efficacy and safety of prophylactic tranexamic acid
administration vs standard uterotonic agents alone among women undergoing cesarean …

Association of tranexamic acid administration with mortality and thromboembolic events in patients with traumatic injury: a systematic review and meta-analysis

V Karl, S Thorn, T Mathes, S Hess… - JAMA network …, 2022 - jamanetwork.com
Importance Tranexamic acid is widely available and used off-label in patients with bleeding
traumatic injury, although the literature does not consistently agree on its efficacy and safety …

Tranexamic acid–a narrative review for the emergency medicine clinician

K Wang, R Santiago - The American Journal of Emergency Medicine, 2022 - Elsevier
Introduction Over the last decade, tranexamic acid (TXA) has been incorporated into
treatment algorithms for a multitude of emergent conditions and the evidence surrounding its …

Effect of preoperative prophylactic intravenous tranexamic acid on perioperative blood loss control in patients undergoing cesarean delivery: a systematic review and …

F Yang, H Wang, M Shen - BMC Pregnancy and Childbirth, 2023 - Springer
Background Postpartum hemorrhage (PPH) is one of the important risk factors leading to
maternal mortality and intervention is essential. Oxytocin therapy is widely used clinically …

Massive hemorrhage protocol: a practical approach to the bleeding trauma patient

A Petrosoniak, K Pavenski, LT da Luz… - Emergency Medicine …, 2023 - emed.theclinics.com
A focused assessment with sonography in trauma examination is positive for free fluid in the
right upper quadrant. There is no evidence of pneumothorax on ultrasound. Her pelvis is …

Prophylactic tranexamic acid among women undergoing vaginal delivery to reduce postpartum blood loss and related morbidities: a systematic review and meta …

A Abu-Zaid, S Baradwan, MS Alshahrani… - Journal of gynecology …, 2022 - Elsevier
Objective To conduct a systematic review and meta-analysis of all randomized controlled
trials (RCTs) that inspected the efficacy and safety of prophylactic TXA compared with …

Efficacy and safety of tranexamic acid in acute haemorrhage

M Franchini, D Focosi, M Zaffanello, PM Mannucci - bmj, 2024 - bmj.com
A 33 year old woman in the fourth month of pregnancy is referred to the emergency
department because of spontaneous massive antepartum haemorrhage. On admission her …

Efficacy and safety of the second in-hospital dose of tranexamic acid after receiving the prehospital dose: double-blind randomized controlled clinical trial in a level 1 …

A El-Menyar, K Ahmed, S Hakim, A Kanbar… - European Journal of …, 2022 - Springer
Background Prehospital administration of tranexamic acid (TXA) to injured patients is
increasing worldwide. However, optimal TXA dose and need of a second infusion on …

[HTML][HTML] Effectiveness of tranexamic acid in trauma patients: a systematic review

KM Monge, SS Domene, DLD Mendoza… - Cureus, 2024 - ncbi.nlm.nih.gov
Tranexamic acid (TXA), a fibrinolytic agent, effectively inhibits plasminogen activation,
thereby reducing fibrinolysis and hemorrhage. This study focused on its application in …

[HTML][HTML] The effectiveness of prehospital administration of tranexamic acid in reducing mortality in trauma patients: an overview

SS Javeed, MA Altawili, LNA Almubarak, SA Alaodah… - Cureus, 2023 - ncbi.nlm.nih.gov
Tranexamic acid (TXA) is an antifibrinolytic drug that reduces bleeding by inhibiting
plasminogen activation and fibrin clot degradation. Its role in prehospital trauma …