Hepatitis B virus (HBV) is a non-cytopathic, hepatotropic virus with the potential to cause a
persistent infection, ultimately leading to cirrhosis and hepatocellular carcinoma. Over the …

Approximately 5% of individuals infected with hepatitis B virus (HBV) are coinfected with
hepatitis D virus (HDV). Chronic HBV/HDV coinfection is associated with an unfavourable …

Chronic hepatitis B virus (HBV) infection is a common cause of liver disease globally, with a
disproportionately high burden in South-East Asia. Vaccines and nucleoside or nucleotide …

Functional cure of chronic hepatitis B (CHB)—or hepatitis B surface antigen (HBsAg) loss
after 24 weeks off therapy—is now the goal of treatment, but is rarely achieved with current …

Human hepatitis B virus (HBV) is the prototype of a family of small DNA viruses that
productively infect hepatocytes, the major cell of the liver, and replicate by reverse …

Interferon (IFN) signaling induces the expression of a wide array of genes, collectively
referred to as IFN-stimulated genes (ISGs) that generally function to inhibit viral replication …

Hepatitis B virus (HBV) infection causes chronic hepatitis and has long term complications.
Individuals ever infected with HBV are at risk of viral reactivation under certain …

Each hepatitis virus—Hepatitis A, B, C, D, E, and G—poses a distinct scenario to the patient
and clinician alike. Since the discovery of each virus, extensive knowledge regarding …

Chronic infection with the Hepatitis B Virus (HBV) is a major cause of liver-related morbidity
and mortality. One peculiar observation in cells infected with HBV (or with closely‑related …

Host innate recognition triggers key immune responses for viral elimination. The sensing
mechanism of hepatitis B virus (HBV), a DNA virus, and the subsequent downstream …