The life of eukaryotic cells requires the transport of lipids between membranes, which are
separated by the aqueous environment of the cytosol. Vesicle-mediated traffic along the …

Healthy cells use autophagy as a general'housekeeping'mechanism and to survive stress,
including stress induced by nutrient deprivation. Autophagy is initiated at the isolation …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Beclin 1, the mammalian orthologue of yeast Atg6, has a central role in autophagy, a
process of programmed cell survival, which is increased during periods of cell stress and …

Scarring of the kidney is a major public health concern, directly promoting loss of kidney
function. To understand the role of microRNA (miRNA) in the progression of kidney scarring …

The study of autophagy is rapidly expanding, and our knowledge of the molecular
mechanism and its connections to a wide range of physiological processes has increased …

There is currently no approved neuroprotective pharmacotherapy for acute conditions such
as stroke and cerebral asphyxia. One of the reasons for this may be the multiplicity of cell …

Autophagy is an important cellular degradation pathway present in all eukaryotic cells. Via
this pathway, portions of the cytoplasm and/or organelles are sequestered in double …

Beclin-1 (the mammalian ortholog of yeast ATG6) has been well-characterized to play a
pivotal role in autophagy that is a major catabolic pathway in which the cell degrades …

As the “master” microRNA that is induced by hypoxia, miR‐210 is involved in multiple
processes in the hypoxia pathway. However, whether miR‐210 mediates hypoxia‐induced …