[HTML][HTML] The serotonin theory of depression: a systematic umbrella review of the evidence
J Moncrieff, RE Cooper, T Stockmann… - Molecular …, 2023 - nature.com
The serotonin hypothesis of depression is still influential. We aimed to synthesise and
evaluate evidence on whether depression is associated with lowered serotonin …
evaluate evidence on whether depression is associated with lowered serotonin …
Rethinking minority stress: A social safety perspective on the health effects of stigma in sexually-diverse and gender-diverse populations
LM Diamond, J Alley - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
For over two decades, the minority stress model has guided research on the health of
sexually-diverse individuals (those who are not exclusively heterosexual) and gender …
sexually-diverse individuals (those who are not exclusively heterosexual) and gender …
The 2020 Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders
Objectives: To provide advice and guidance regarding the management of mood disorders,
derived from scientific evidence and supplemented by expert clinical consensus to formulate …
derived from scientific evidence and supplemented by expert clinical consensus to formulate …
Reflecting on rumination: Consequences, causes, mechanisms and treatment of rumination
ER Watkins, H Roberts - Behaviour research and therapy, 2020 - Elsevier
We review research showing that rumination has multiple negative consequences:(a)
exacerbating psychopathology by magnifying and prolonging negative mood states …
exacerbating psychopathology by magnifying and prolonging negative mood states …
Suicide and suicide risk
Although recent years have seen large decreases in the overall global rate of suicide
fatalities, this trend is not reflected everywhere. Suicide and suicidal behaviour continue to …
fatalities, this trend is not reflected everywhere. Suicide and suicidal behaviour continue to …
No support for historical candidate gene or candidate gene-by-interaction hypotheses for major depression across multiple large samples
Objective: Interest in candidate gene and candidate gene-by-environment interaction
hypotheses regarding major depressive disorder remains strong despite controversy …
hypotheses regarding major depressive disorder remains strong despite controversy …
The devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders
ETC Lippard, CB Nemeroff - American journal of psychiatry, 2020 - Am Psychiatric Assoc
A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …
stage of development can have long-lasting consequences. It is associated with a marked …
[HTML][HTML] Early life adversity shapes neural circuit function during sensitive postnatal developmental periods
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
[HTML][HTML] Developmental trajectories of early life stress and trauma: a narrative review on neurobiological aspects beyond stress system dysregulation
Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …
Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …