The immune system and cancer have a complex relationship with the immune system
playing a dual role in tumor development. The effector cells of the immune system can …

Lymphocytes involved in intestinal immune response are found in organized immune
inductive sites of the gut-associated lymphoid tissues (GALT) such as Peyer's patches (PP) …

Regulatory T cells (Treg cells) can activate multiple suppressive mechanisms in vitro after
activation via the T cell antigen receptor, resulting in antigen-independent suppression …

The phenotypic characterization of the cells in which HIV persists during antiretroviral
therapy (ART) remains technically challenging. We developed a simple flow cytometry …

The integrin α4β1 (VLA-4) is used by encephalitogenic T cells to enter the central nervous
system (CNS). However, both Th1 and Th17 cells are capable of inducing experimental …

To become activated, T cells must efficiently recognize antigen-presenting cells or target
cells through several complex cytoskeleton-dependent processes, including integrin …

The tetraspanin CD9 is expressed by all the major subsets of leukocytes (B cells, CD4+ T
cells, CD8+ T cells, natural killer cells, granulocytes, monocytes and macrophages, and …

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS)
caused by CNS-infiltrating leukocytes, including TH17 cells that are critical mediators of …

The paracaspase MALT1 is pivotal in antigen receptor–mediated lymphocyte activation and
lymphomagenesis. MALT1 contains a caspase-like domain, but it is unknown whether this …

Regulatory T cells (Treg) are known to be critical for the maintenance of immune
homeostasis by suppressing the activation of auto-or allo-reactive effector T cells through a …