Acylcarnitines: nomenclature, biomarkers, therapeutic potential, drug targets, and clinical trials

M Dambrova, M Makrecka-Kuka, J Kuka… - Pharmacological …, 2022 - ASPET
Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …

[HTML][HTML] Metabolic and vascular effect of the Mediterranean diet

A Tuttolomondo, I Simonetta, M Daidone… - International journal of …, 2019 - mdpi.com
Several studies indicated how dietary patterns that were obtained from nutritional cluster
analysis can predict disease risk or mortality. Low-grade chronic inflammation represents a …

Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome …

V Meslier, M Laiola, F De Filippis, H Roume… - Gut, 2020 - gut.bmj.com
Objectives This study aimed to explore the effects of an isocaloric Mediterranean diet (MD)
intervention on metabolic health, gut microbiome and systemic metabolome in subjects with …

The Mediterranean diet, plasma metabolome, and cardiovascular disease risk

J Li, M Guasch-Ferré, W Chung… - European heart …, 2020 - academic.oup.com
Aims To investigate whether metabolic signature composed of multiple plasma metabolites
can be used to characterize adherence and metabolic response to the Mediterranean diet …

Benefits of the Mediterranean diet: Epidemiological and molecular aspects

L Serra-Majem, B Roman-Vinas… - Molecular aspects of …, 2019 - Elsevier
More than 50 years after the Seven Countries Study, a large number of epidemiological
studies have explored the relationship between the Mediterranean diet (MD) and health …

[HTML][HTML] Plasma metabolomic profiles associated with mortality and longevity in a prospective analysis of 13,512 individuals

F Wang, AJ Tessier, L Liang, C Wittenbecher… - Nature …, 2023 - nature.com
Experimental studies reported biochemical actions underpinning aging processes and
mortality, but the relevant metabolic alterations in humans are not well understood. Here we …

[HTML][HTML] High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies

HB Beyene, G Olshansky, AA T. Smith, C Giles… - PLoS …, 2020 - journals.plos.org
Obesity and related metabolic diseases show clear sex-related differences. The growing
burden of these diseases calls for better understanding of the age-and sex-related metabolic …

[HTML][HTML] Mediterranean diet and prevention of chronic diseases

DF Romagnolo, OI Selmin - Nutrition today, 2017 - journals.lww.com
A large body of research data suggests that traditional dietary habits and lifestyle unique to
the Mediterranean region (Mediterranean diet, MD) lower the incidence of chronic diseases …

[HTML][HTML] Metabolome changes in cerebral ischemia

TH Shin, DY Lee, S Basith, B Manavalan, MJ Paik… - Cells, 2020 - mdpi.com
Cerebral ischemia is caused by perturbations in blood flow to the brain that trigger
sequential and complex metabolic and cellular pathologies. This leads to brain tissue …

[HTML][HTML] Olive oil and prevention of chronic diseases: Summary of an International conference

F Visioli, M Franco, E Toledo, J Luchsinger… - Nutrition, Metabolism …, 2018 - Elsevier
Olive oil is the foremost source of fat in the Mediterranean area and, among other features,
sets the Mediterranean diet apart from other dietary regimens. In January 2018, the …