The aging lung

EM Lowery, AL Brubaker, E Kuhlmann… - Clinical interventions in …, 2013 - Taylor & Francis
There are many age-associated changes in the respiratory and pulmonary immune system.
These changes include decreases in the volume of the thoracic cavity, reduced lung …

Mucociliary clearance in the airways.

A Wanner, M Salathé, TG O'Riordan - American journal of …, 1996 - atsjournals.org
The ventilation of the lung ranges between 1,000 and 21,000 liters per 24 hours in humans
depending on body size and physical activity. This exposes the extensive epithelial surface …

[图书][B] Hayes' principles and methods of toxicology

AW Hayes, T Kobets - 2023 - taylorfrancis.com
Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

[图书][B] Tobacco smoke and involuntary smoking

IARC Working Group on the Evaluation of … - 2004 - books.google.com
The IARC Monographs series publishes authoritative independent assessments by
international experts of the carcinogenic risks posed to humans by a variety of agents …

Deposition, retention, and clearance of inhaled particles.

M Lippmann, DB Yeates, RE Albert - Occupational and Environmental …, 1980 - oem.bmj.com
The relation between the concentrations and characteristics of air contaminants in the work
place and the resultant toxic doses and potential hazards after their inhalation depends …

Nasal mucociliary clearance as a factor in nasal drug delivery

E Marttin, NGM Schipper, JC Verhoef… - Advanced drug delivery …, 1998 - Elsevier
The nasal mucociliary clearance system transports the mucus layer that covers the nasal
epithelium towards the nasopharynx by ciliary beating. Its function is to protect the …

Managing cough as a defense mechanism and as a symptom: a consensus panel report of the American College of Chest Physicians

RS Irwin, LP Boulet, MM Cloutier, R Fuller, PM Gold… - Chest, 1998 - journal.chestnet.org
1. Cough can (a) be an important defense mechanism to help clear excessive secretions
and foreign material from airways;(b) be an important factor in the spread of infection;(c) …

Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack

T Aikawa, S Shimura, H Sasaki, M Ebina, T Takishima - Chest, 1992 - Elsevier
To examine the changes in airways in bronchial asthma (BA) during an asthma attack
causing death, we performed morphometric analysis of autopsied lungs from three …

Elderly patients and management in intensive care units (ICU): clinical challenges

LB Brunker, CS Boncyk, KF Rengel… - Clinical interventions in …, 2023 - Taylor & Francis
There is a growing population of older adults requiring admission to the intensive care unit
(ICU). This population outpaces the ability of clinicians with geriatric training to assist in their …

Smoking is associated with shortened airway cilia

PL Leopold, MJ O'Mahony, XJ Lian, AE Tilley… - PloS one, 2009 - journals.plos.org
Background Whereas cilia damage and reduced cilia beat frequency have been implicated
as causative of reduced mucociliary clearance in smokers, theoretically mucociliary …