Utilizing 4D printing to design smart gastroretentive, esophageal, and intravesical drug delivery systems

DB Mahmoud… - Advanced Healthcare …, 2023 - Wiley Online Library
The breakthrough of 3D printing in biomedical research has paved the way for the next
evolutionary step referred to as four dimensional (4D) printing. This new concept utilizes the …

Thiolated chitosans: A multi-talented class of polymers for various applications

C Federer, M Kurpiers… - Biomacromolecules, 2020 - ACS Publications
Various properties of chitosan can be customized by thiolation for very specific needs in a
wide range of application areas. Since the discovery of thiolated chitosans, many studies …

Current status of the development of intravesical drug delivery systems for the treatment of bladder cancer

HY Yoon, HM Yang, CH Kim, YT Goo… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Intravesical instillation is preferred over the systemic route of administration, as
an efficient route of drug administration to treat bladder cancer. However, the periodic …

Thiolated-polymer-based nanoparticles as an avant-garde approach for anticancer therapies—reviewing thiomers from chitosan and hyaluronic acid

R Grosso, MV de-Paz - Pharmaceutics, 2021 - mdpi.com
Thiomers (or thiolated polymers) have broken through as avant-garde approaches in
anticancer therapy. Their distinguished reactivity and properties, closely linked to their final …

Thiolated nanoparticles for biomedical applications: mimicking the workhorses of our body

N Hock, GF Racaniello, S Aspinall, N Denora… - Advanced …, 2022 - Wiley Online Library
Advances in nanotechnology have generated a broad range of nanoparticles (NPs) for
numerous biomedical applications. Among the various properties of NPs are functionalities …

A systematic review of therapeutic approaches used in experimental models of interstitial cystitis/bladder pain syndrome

T Kuret, D Peskar, A Erman, P Veranič - Biomedicines, 2021 - mdpi.com
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a multifactorial, chronic bladder
disorder with limited therapeutic options currently available. The present review provides an …

Mucoadhesive polymers and their applications in drug delivery systems for the treatment of bladder cancer

CSA de Lima, JPRO Varca, VM Alves, KM Nogueira… - Gels, 2022 - mdpi.com
Bladder cancer (BC) is the tenth most common type of cancer worldwide, affecting up to four
times more men than women. Depending on the stage of the tumor, different therapy …

Design of virus-mimicking polyelectrolyte complexes for enhanced oral insulin delivery

C Liu, H Xu, Y Sun, X Zhang, H Cheng… - Journal of Pharmaceutical …, 2019 - Elsevier
The viscous and elastic mucus layer is still an undesirable barrier for oral insulin delivery. To
solve the problem, virus-mimicking nanosized polyelectrolyte complex (PEC) was designed …

Mucoadhesive polymers: Gateway to innovative drug delivery

M Yaqoob, A Jalil, A Bernkop-Schnürch - Modeling and Control of Drug …, 2021 - Elsevier
Mucoadhesion is a complex process that is mainly provided by the polymers. It involves
wetting, adsorption, and interpenetration of polymer chains among other processes …

Self-emulsifying drug delivery system enhances tissue distribution of cinnamaldehyde by altering the properties of the mucus layer

L Liu, W Cao, M Xia, C Tian, W Wu, Y Cai, X Chu - AAPS PharmSciTech, 2022 - Springer
Oral delivery is considered the preferred route of administration due to its convenience and
favorable compliance. However, this delivery often faces difficulties, such as poor solubility …