Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells
N Mironova, I Petrushanko, O Patutina, AV Sen'kova… - Cell Cycle, 2013 - Taylor & Francis
Exogenous ribonucleases are known to inhibit tumor growth via apoptosis induction in tumor
cells, allowing to consider them as promising anticancer drugs for clinical application. In this …
cells, allowing to consider them as promising anticancer drugs for clinical application. In this …
Three‐step procedure for preparation of pure Bacillus altitudinis ribonuclease
Ribonucleases are considered as promising tools for anticancer treatment due to their
selective cytotoxicity against tumor cells. We investigated a new RN ase from Bacillus …
selective cytotoxicity against tumor cells. We investigated a new RN ase from Bacillus …
Binase immobilized on halloysite nanotubes exerts enhanced cytotoxicity toward human colon adenocarcinoma cells
V Khodzhaeva, A Makeeva, V Ulyanova… - Frontiers in …, 2017 - frontiersin.org
Many ribonucleases (RNases) are considered as promising tools for antitumor therapy
because of their selective cytotoxicity toward cancer cells. Binase, the RNase from Bacillus …
because of their selective cytotoxicity toward cancer cells. Binase, the RNase from Bacillus …
[HTML][HTML] Binase treatment increases interferon sensitivity and apoptosis in SiHa cervical carcinoma cells by downregulating E6 and E7 human papilloma virus …
VA Mitkevich, KM Burnysheva, IY Petrushanko… - Oncotarget, 2017 - ncbi.nlm.nih.gov
In this study, we determined whether binase, a ribonuclease from Bacillus pumilus,
increases interferon sensitivity and apoptosis in SiHa cervical cancer cells infected with high …
increases interferon sensitivity and apoptosis in SiHa cervical cancer cells infected with high …
Bacillus intermedius ribonuclease (BINASE) induces apoptosis in human ovarian cancer cells
AR Garipov, AA Nesmelov, HA Cabrera-Fuentes… - Toxicon, 2014 - Elsevier
The cytotoxic effects of Bacillus intermedius RNase (binase) towards ovarian cancer cells
(SKOV3 and OVCAR5) were studied in comparison to normal ovarian epithelial cells …
(SKOV3 and OVCAR5) were studied in comparison to normal ovarian epithelial cells …
Antitumour Activity of the Ribonuclease Binase from Bacillus pumilus in the RLS40 Tumour Model Is Associated with the Reorganisation of the miRNA Network and …
ISE Mohamed, AV Sen'kova, AI Nadyrova, IA Savin… - Biomolecules, 2020 - mdpi.com
The important role of miRNA in cell proliferation and differentiation has raised interest in
exogenous ribonucleases (RNases) as tools to control tumour-associated intracellular and …
exogenous ribonucleases (RNases) as tools to control tumour-associated intracellular and …
RNases disrupt the adaptive potential of malignant cells: perspectives for therapy
VA Mitkevich, IY Petrushanko… - Frontiers in Pharmacology, 2019 - frontiersin.org
Exogenous RNases are selectively toxic to tumor cells. The reasons for this selectivity are
not quite clear and should be searched for in the properties that distinguish malignant from …
not quite clear and should be searched for in the properties that distinguish malignant from …
Combination of RNase Binase and AKT1/2 Kinase Inhibitor Blocks Two Alternative Survival Pathways in Kasumi-1 Cells
VA Mitkevich, IY Petrushanko, MG Engelhardt… - Molecular Biology, 2022 - Springer
Abstract Treatment of malignant neoplasms often requires the use of combinations of
chemotherapeutic agents. However, in order to select combinations that are effective against …
chemotherapeutic agents. However, in order to select combinations that are effective against …
[PDF][PDF] Механизмы подавления прогрессии экспериментальных опухолей под действием дендритных клеток и природных нуклеаз
НЛ Миронова - Дис. док. биол. наук - niboch.nsc.ru
Развитие опухоли сопровождается быстрой пролиферацией, потерей
дифференциации, развитием устойчивости опухолевых клеток к гибели …
дифференциации, развитием устойчивости опухолевых клеток к гибели …
[PDF][PDF] Binase Immobilized on halloysite nanotubes exerts enhanced cytotoxicity toward human colon adenocarcinoma cells
R Fakhrullin, O Ilinskaya - 2017 - core.ac.uk
Abstract© 2017 Khodzhaeva, Makeeva, Ulyanova. Many ribonucleases (RNases) are
considered as promising tools for antitumor therapy because of their selective cytotoxicity …
considered as promising tools for antitumor therapy because of their selective cytotoxicity …