Exogenous ribonucleases are known to inhibit tumor growth via apoptosis induction in tumor
cells, allowing to consider them as promising anticancer drugs for clinical application. In this …

Ribonucleases are considered as promising tools for anticancer treatment due to their
selective cytotoxicity against tumor cells. We investigated a new RN ase from Bacillus …

Many ribonucleases (RNases) are considered as promising tools for antitumor therapy
because of their selective cytotoxicity toward cancer cells. Binase, the RNase from Bacillus …

In this study, we determined whether binase, a ribonuclease from Bacillus pumilus,
increases interferon sensitivity and apoptosis in SiHa cervical cancer cells infected with high …

The cytotoxic effects of Bacillus intermedius RNase (binase) towards ovarian cancer cells
(SKOV3 and OVCAR5) were studied in comparison to normal ovarian epithelial cells …

The important role of miRNA in cell proliferation and differentiation has raised interest in
exogenous ribonucleases (RNases) as tools to control tumour-associated intracellular and …

Exogenous RNases are selectively toxic to tumor cells. The reasons for this selectivity are
not quite clear and should be searched for in the properties that distinguish malignant from …

Abstract Treatment of malignant neoplasms often requires the use of combinations of
chemotherapeutic agents. However, in order to select combinations that are effective against …

Развитие опухоли сопровождается быстрой пролиферацией, потерей
дифференциации, развитием устойчивости опухолевых клеток к гибели …

Abstract© 2017 Khodzhaeva, Makeeva, Ulyanova. Many ribonucleases (RNases) are
considered as promising tools for antitumor therapy because of their selective cytotoxicity …