Metabolic reprogramming is involved in the pathogenesis of not only cancers but also
neurodegenerative diseases, cardiovascular diseases, and infectious diseases. With the …

Protein lipidation, including cysteine prenylation, N-terminal glycine myristoylation, cysteine
palmitoylation, and serine and lysine fatty acylation, occurs in many proteins in eukaryotic …

Protein S-acylation, the only fully reversible posttranslational lipid modification of proteins, is
emerging as a ubiquitous mechanism to control the properties and function of a diverse …

The lipid post‐translational modification S‐palmitoylation is a vast developing field, with the
modification itself and the enzymes that catalyse the reversible reaction implicated in a …

In the past few decades, the field of neuroepigenetics has investigated how the brain
encodes information to form long-lasting memories that lead to stable changes in behaviour …

The serotonergic system and in particular serotonin 1A receptor (5-HT1AR) are implicated in
major depressive disorder (MDD). Here we demonstrated that 5-HT1AR is palmitoylated in …

Mutations are at the root of many human diseases. Still, we largely do not exactly
understand how they trigger pathogenesis. One, more recent, hypothesis has been that they …

Post-translational attachment of lipids to proteins is found in all organisms, and is important
for many biological processes. Acylation with myristic and palmitic acids are among the most …

Posttranslational modifications of proteins are important regulatory processes endowing the
proteins functional complexity. Over the last decade, numerous studies have shed light on …

Many postsynaptic proteins undergo palmitoylation, the reversible attachment of the fatty
acid palmitate to cysteine residues, which influences trafficking, localization, and protein …