miRNA targets: from prediction tools to experimental validation

G Riolo, S Cantara, C Marzocchi, C Ricci - Methods and protocols, 2020 - mdpi.com
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression in both animals
and plants. By pairing to microRNA responsive elements (mREs) on target mRNAs, miRNAs …

Helminth extracellular vesicles in host–parasite interactions

L Tritten, TG Geary - Current opinion in microbiology, 2018 - Elsevier
Extracellular vesicles (EVs) have been characterized from many species of parasitic
helminths, and recent experimental evidence supports important functions for their cargo in …

An updated overview and classification of bioinformatics tools for MicroRNA analysis, which one to choose?

SS Mortazavi, Z Bahmanpour… - Computers in biology …, 2021 - Elsevier
Abstract The term 'MicroRNA'(miRNA) refers to a class of small endogenous non-coding
RNAs (ncRNAs) regenerated from hairpin transcripts. Recent studies reveal miRNAs' …

Detecting and characterizing A-To-I microRNA editing in cancer

GP Marceca, L Tomasello, R Distefano, M Acunzo… - Cancers, 2021 - mdpi.com
Simple Summary Adenosine to inosine (A-to-I) editing is a type of RNA editing where
individual adenosines are enzymatically converted into inosines. A-to-I RNA editing plays an …

Unveiling ncRNA regulatory axes in atherosclerosis progression

E Navarro, A Mallén, JM Cruzado, J Torras… - Clinical and translational …, 2020 - Springer
Completion of the human genome sequencing project highlighted the richness of the
cellular RNA world, and opened the door to the discovery of a plethora of short and long non …

[HTML][HTML] Prediction of the miRNA interactome–established methods and upcoming perspectives

M Schäfer, C Ciaudo - Computational and structural biotechnology journal, 2020 - Elsevier
MicroRNAs (miRNAs) are well-studied small noncoding RNAs involved in post-
transcriptional gene regulation in a wide range of organisms, including mammals. Their …

Robust partitioning of microRNA targets from downstream regulatory changes

RK Patel, JD West, Y Jiang, EA Fogarty… - Nucleic acids …, 2020 - academic.oup.com
The biological impact of microRNAs (miRNAs) is determined by their targets, and robustly
identifying direct miRNA targets remains challenging. Existing methods suffer from high false …

Recent development of bioinformatics tools for microRNA target prediction

MS Khatun, MA Alam, W Shoombuatong… - Current medicinal …, 2022 - ingentaconnect.com
MicroRNAs (miRNAs) are central players that regulate the post-transcriptional processes of
gene expression. Binding of miRNAs to target mRNAs can repress their translation by …

MicroRNAs from saliva of anopheline mosquitoes mimic human endogenous miRNAs and may contribute to vector-host-pathogen interactions

B Arcà, A Colantoni, C Fiorillo, F Severini, V Benes… - Scientific Reports, 2019 - nature.com
During blood feeding haematophagous arthropods inject into their hosts a cocktail of
salivary proteins whose main role is to counteract host haemostasis, inflammation and …

[PDF][PDF] RETRACTED: Long Non-Coding RNA ELFN1-AS1 Promoted Colon Cancer Cell Growth and Migration via the miR-191-5p/Special AT-Rich Sequence-Binding …

Y Du, Y Hou, Y Shi, J Liu, T Li - Frontiers in oncology, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) are reported to participate in tumor development. It has
been manifested in previous researches that lncRNA ELFN1-AS1 is involved in early-stage …