Background The function of the thymus in human adults is unclear, and routine removal of
the thymus is performed in a variety of surgical procedures. We hypothesized that the adult …

The paraneoplastic neurologic disorders (PND) are a diverse group of diseases
characterized by the presence of neurologic dysfunction in the setting of a remote cancer …

The course of myasthenia gravis (MG) may get complicated by the development of other
autoimmune diseases. Estimates of the frequency of autoimmune diseases will help inform …

The thymus is critical for central tolerance and diverse T-lymphocyte repertoire development,
to provide lifelong defense against pathogens while maintaining self-tolerance. Peak thymic …

Background and Purpose Myasthenia gravis (MG) is usually comorbid with thymoma. More
accurate estimates of the incidence thymoma in MG will help inform patients and their …

BACKGROUND: Myasthenia gravis (MG) is an autoimmune disease caused by the action of
specific antibodies to the postsynaptic membrane of the neuromuscular junction, leading to …

OBJECTIVES Although thymoma is considered a relatively indolent neoplasia, patients
affected by this disease are at high risk of developing second tumours (STs). The aim of this …

The thymus plays a pivotal role in generating a highly-diverse repertoire of T lymphocytes
while preventing autoimmunity. Thymus seeding progenitors (TSPs) are a heterogeneous …

Objective: As the number of elderly patients with myasthenia gravis (MG) has recently
increased in Europe and the USA, a retrospective survey of Japanese MG patients was …

Activated cytotoxic CD4 T cells (HLA-DR+) play an important role in the control of EBV
infection, especially in cells with latency I (EBNA-1). One of the evasion mechanisms of …