Epigenetics of male infertility: the role of DNA methylation

JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

Spermatogenesis in humans and its affecting factors

FTL Neto, PV Bach, BB Najari, PS Li… - Seminars in cell & …, 2016 - Elsevier
Spermatogenesis is an extraordinary complex process. The differentiation of spermatogonia
into spermatozoa requires the participation of several cell types, hormones, paracrine …

Nutrigenetics, epigenetics and gestational diabetes: consequences in mother and child

M Franzago, F Fraticelli, L Stuppia, E Vitacolonna - Epigenetics, 2019 - Taylor & Francis
ABSTRACT Gestational Diabetes Mellitus (GDM) is the most common metabolic condition
during pregnancy and may result in short-and long-term complications for both mother and …

Epigenetics in male reproduction: effect of paternal diet on sperm quality and offspring health

U Schagdarsurengin, K Steger - Nature Reviews Urology, 2016 - nature.com
Epigenetic inheritance and its underlying molecular mechanisms are among the most
intriguing areas of current biological and medical research. To date, studies have shown that …

[PDF][PDF] Oxidative stress: Major executioner in disease pathology, role in sperm DNA damage and preventive strategies

S Bisht, R Dada - Front Biosci (Schol Ed), 2017 - researchgate.net
Oxidative stress (OS) has been implicated in a wide array of diseases such as
neurodegenerative disorders, autoimmune diseases, complex lifestyle diseases and cancer …

Genes and diet in the prevention of chronic diseases in future generations

M Franzago, D Santurbano, E Vitacolonna… - International journal of …, 2020 - mdpi.com
Nutrition is a modifiable key factor that is able to interact with both the genome and
epigenome to influence human health and fertility. In particular, specific genetic variants can …

From silent spring to silent night: Agrochemicals and the anthropocene

TB Hayes, M Hansen - Elem Sci Anth, 2017 - online.ucpress.edu
We are now living in the Anthropocene, the first time in Earth's history when synthetic
chemicals—created by humans—are damaging the planet and contributing to a major loss …

Transgenerational epigenetic influences of paternal environmental exposures on brain function and predisposition to psychiatric disorders

S Yeshurun, AJ Hannan - Molecular Psychiatry, 2019 - nature.com
In recent years, striking new evidence has demonstrated non-genetic inheritance of
acquired traits associated with parental environmental exposures. In particular, this …

Oxidative stress and alterations in DNA methylation: two sides of the same coin in reproduction

YJR Menezo, E Silvestris, B Dale, K Elder - Reproductive biomedicine …, 2016 - Elsevier
The negative effect of oxidative stress on the human reproductive process is no longer a
matter for debate. Oxidative stress affects female and male gametes and the developmental …

Heat stress responses in spermatozoa: Mechanisms and consequences for cattle fertility

MB Rahman, K Schellander, NL Luceno, A Van Soom - Theriogenology, 2018 - Elsevier
Currently, the world is facing the negative impact of global warming on all living beings.
Adverse effects of global warming are also becoming obvious in dairy cattle breeding. In …