[HTML][HTML] The many faces of cobalamin (vitamin B12) deficiency

BHR Wolffenbuttel, HJCM Wouters… - Mayo clinic proceedings …, 2019 - Elsevier
Although cobalamin (vitamin B 12) deficiency was described over a century ago, it is still
difficult to establish the correct diagnosis and prescribe the right treatment. Symptoms …

[HTML][HTML] Biomarkers of Nutrition for Development (BOND): vitamin B-12 review

LH Allen, JW Miller, L De Groot, IH Rosenberg… - The Journal of …, 2018 - Elsevier
This report on vitamin B-12 (B12) is part of the Biomarkers of Nutrition for Development
(BOND) Project, which provides state-of-the art information and advice on the selection, use …

Should vitamin B12 status be considered in assessing risk of neural tube defects?

AM Molloy - Annals of the New York Academy of Sciences, 2018 - Wiley Online Library
There is a strong biological premise for including vitamin B12 with folic acid in strategies to
prevent neural tube defects (NTDs), due to the closely interlinked metabolism of these two …

Fucosyltransferase 2: a genetic risk factor for primary sclerosing cholangitis and Crohn's disease—a comprehensive review

L Maroni, SFJ van de Graaf, SD Hohenester… - Clinical reviews in …, 2015 - Springer
Abstract Fucosyltransferase 2 (FUT2) mediates the inclusion of fucose in sugar moieties of
glycoproteins and glycolipids. ABO blood group antigens and host-microbe interactions are …

Vitamin B12

BHR Wolffenbuttel, PJ Owen, M Ward, R Green - bmj, 2023 - bmj.com
• The clinical picture is the most important factor in assessing the significance of results of
blood tests assessing cobalamin (B12) status because there is no “gold standard” test to …

[HTML][HTML] Modeling a methylmalonic acid–derived change point for serum vitamin B-12 for adults in NHANES

RL Bailey, RA Durazo-Arvizu, R Carmel… - The American journal of …, 2013 - Elsevier
Background: No consensus exists about which cutoff point should be applied for serum
vitamin B-12 (SB-12) concentrations to define vitamin B-12 status in population-based …

Whole Genome Sequencing of Mycobacterium africanum Strains from Mali Provides Insights into the Mechanisms of Geographic Restriction

K Winglee, A Manson McGuire, M Maiga… - PLoS neglected …, 2016 - journals.plos.org
Background Mycobacterium africanum, made up of lineages 5 and 6 within the
Mycobacterium tuberculosis complex (MTC), causes up to half of all tuberculosis cases in …

Improving maternal folate status to prevent infant neural tube defects: working group conclusions and a framework for action

H Martinez, AP Weakland, LB Bailey… - Annals of the new …, 2018 - Wiley Online Library
As infectious disease control programs achieve increasing success, further reductions in
child mortality in low‐and middle‐income countries (LMICs) will require focused prevention …

The FUT2 secretor variant p.Trp154Ter influences serum vitamin B12 concentration via holo-haptocorrin, but not holo-transcobalamin, and is associated with …

A Velkova, JEL Diaz, F Pangilinan… - Human molecular …, 2017 - academic.oup.com
Vitamin B12 deficiency is common in older individuals. Circulating vitamin B12
concentration can be used to diagnose deficiency, but this test has substantial false positive …

Exome-wide association study identifies new low-frequency and rare UGT1A1 coding variants and UGT1A6 coding variants influencing serum bilirubin in elderly …

A Oussalah, P Bosco, G Anello, R Spada… - Medicine, 2015 - journals.lww.com
Genome-wide association studies (GWASs) have identified loci contributing to total serum
bilirubin level. However, no exome-wide approaches have been performed to address this …