Colchicine—update on mechanisms of action and therapeutic uses

YY Leung, LLY Hui, VB Kraus - Seminars in arthritis and rheumatism, 2015 - Elsevier
Objectives To review the literature and provide an update on the mechanisms of action and
therapeutic uses of oral colchicine in arthritis and inflammatory conditions. Methods We …

Behçet's disease: new insights into pathophysiology, clinical features and treatment options

A Greco, A De Virgilio, M Ralli, A Ciofalo, P Mancini… - Autoimmunity …, 2018 - Elsevier
Behçet's disease (BD) is a rare systemic vasculitis characterized by oral aphthous ulcers,
genital ulcers, ocular lesions and other systemic manifestations. BD occurs most frequently …

2018 update of the EULAR recommendations for the management of Behçet's syndrome

G Hatemi, R Christensen, D Bang, B Bodaghi… - Annals of the …, 2018 - ard.bmj.com
Several new treatment modalities with different mechanisms of action have been studied in
patients with Behçet's syndrome (BS). The aim of the current effort was to update the …

Behcet's disease: A comprehensive review with a focus on epidemiology, etiology and clinical features, and management of mucocutaneous lesions

E Alpsoy - The Journal of dermatology, 2016 - Wiley Online Library
Behçet's disease (BD) is a chronic, relapsing, inflammatory multisystem disease of unknown
etiology. Oral ulcers, genital ulcers, cutaneous lesions, and ocular and articular involvement …

[HTML][HTML] Adverse events during oral colchicine use: a systematic review and meta-analysis of randomised controlled trials

S Stewart, KCK Yang, K Atkins, N Dalbeth… - Arthritis research & …, 2020 - Springer
Background Colchicine is a widely used drug to treat inflammatory diseases. Due to its long
historical use in medicine, controlled clinical trials have been small and there remains some …

Colchicine: an ancient drug with novel applications

B Dasgeb, D Kornreich, K McGuinn… - British Journal of …, 2018 - academic.oup.com
Colchicine is a treatment for gout that has been used for more than a millennium. It is the
treatment of choice for familial Mediterranean fever and its associated complication …

Colchicine: old and new

A Slobodnick, B Shah, MH Pillinger… - The American journal of …, 2015 - Elsevier
Although colchicine has been a focus of research, debate, and controversy for thousands of
years, the US Food and Drug Administration just approved it in 2009. Over the past decade …

Neutrophilic dermatoses: pathogenesis, Sweet syndrome, neutrophilic eccrine hidradenitis, and Behçet disease

CA Nelson, S Stephen, HJ Ashchyan… - Journal of the American …, 2018 - Elsevier
Neutrophilic dermatoses are a heterogeneous group of inflammatory skin disorders that
present with unique clinical features but are unified by the presence of a sterile …

Apremilast for Behçet's syndrome—a phase 2, placebo-controlled study

G Hatemi, M Melikoglu, R Tunc… - … England Journal of …, 2015 - Mass Medical Soc
Background Oral ulcers, the hallmark of Behçet's syndrome, can be resistant to conventional
treatment; therefore, alternative agents are needed. Apremilast is an oral phosphodiesterase …

[HTML][HTML] Behcet's disease: review with emphasis on dermatological aspects

MAR Scherrer, VB Rocha, LC Garcia - Anais brasileiros de …, 2017 - SciELO Brasil
Behçet's disease is a systemic vasculitis characterized by attacks of acute inflammation,
which can affect almost every vascularized area of the body. There is a close correlation …