Immune Sensing of Candida albicans

E Bojang, H Ghuman, P Kumwenda, RA Hall - Journal of Fungi, 2021 - mdpi.com
Candida albicans infections range from superficial to systemic and are one of the leading
causes of fungus-associated nosocomial infections. The innate immune responses during …

The Role of B-Cells and Antibodies against Candida Vaccine Antigens in Invasive Candidiasis

M Shukla, P Chandley, S Rohatgi - Vaccines, 2021 - mdpi.com
Systemic candidiasis is an invasive fungal infection caused by members of the genus
Candida. The recent emergence of antifungal drug resistance and increased incidences of …

Host-pathogen interactions between the human innate immune system and Candida albicans—understanding and modeling defense and evasion strategies

S Dühring, S Germerodt, C Skerka, PF Zipfel… - Frontiers in …, 2015 - frontiersin.org
The diploid, polymorphic yeast Candida albicans is one of the most important human
pathogenic fungi. C. albicans can grow, proliferate and coexist as a commensal on or within …

Interleukin-1β induces CXCR3-mediated chemotaxis to promote umbilical cord mesenchymal stem cell transendothelial migration

YC Guo, YH Chiu, CP Chen, HS Wang - Stem cell research & therapy, 2018 - Springer
Abstract Background Mesenchymal stem cells (MSCs) are known to home to injured and
inflamed regions via the bloodstream to assist in tissue regeneration in response to signals …

Immunopathogenesis of Emerging Candida auris and Candida haemulonii Strains

S Pharkjaksu, N Boonmee, C Mitrpant… - Journal of Fungi, 2021 - mdpi.com
The emergence of a multidrug-resistant Candida species, C. auris and C. haemulonii, has
been reported worldwide. In Thailand, information on them is limited. We collected clinical …

In vitro and in vivo efficacies of Dectin-1-Fc(IgG)(s) fusion proteins against invasive fungal infections

S Ruiz Mendoza, SC Liedke… - Medical …, 2022 - academic.oup.com
Fungal infections have increased in the last years, particularly associated to an increment in
the number of immunocompromised individuals and the emergence of known or new …

TLR-2, IL-10 and IL-17-mediated immunity in experimental chemotherapy murine model of systemic candidiasis; cyclophosphamides' impact and roles

P Dehghan, S Tolouie, B Baradaran, S Nami… - Microbial …, 2018 - Elsevier
The majority of immune components such as Toll-like receptor (TLR)-2, interleukin (IL)-17,
neutrophils, and IL-10 play pivotal roles in immunity to Candida albicans (C. albicans) …

ERG3-Encoding Sterol C5,6-DESATURASE in Candida albicans Is Required for Virulence in an Enterically Infected Invasive Candidiasis Mouse Model

T Hirayama, T Miyazaki, M Sumiyoshi, N Ashizawa… - Pathogens, 2020 - mdpi.com
Gastrointestinal colonization by Candida species is considered the main source of
candidemia. The ERG3 gene in Candida albicans encodes a sterol C5, 6-desaturase, which …

Difference in immune responses to Candida albicans in two inbred strains of male rats

MV Papic, B Ljujic, S Zivanovic, M Papic, M Vuletic… - Archives of Oral …, 2023 - Elsevier
Objective To investigate the influence of strain differences in immune response on the
pathogenesis of oral candidiasis in Dark Agouti (DA) and Albino Oxford (AO) inbred strains …

Callophycin A loaded chitosan and spicules based nanocomposites as an alternative strategy to overcome vaginal candidiasis

G Arumugam, R Rajendran - International Journal of Biological …, 2020 - Elsevier
The present study aimed to understand the killing effects of seaweed derived metabolite
Callophycin A (Cal A). In vitro studies confirmed that the beneficial effects of Cal A on the …