DNA methylation is of paramount importance for mammalian embryonic development. DNA
methylation has numerous functions: it is implicated in the repression of transposons and …

Single-cell sequencing-based methods for profiling gene transcript levels have revealed
substantial heterogeneity in expression levels among morphologically indistinguishable …

The DNA methyltransferase (DNMT) family comprises a conserved set of DNA-modifying
enzymes that have a central role in epigenetic gene regulation. Recent studies have shown …

Dynamic binding of transcription factors (TFs) to regulatory elements controls transcriptional
states throughout organism development. Epigenetics modifications, such as DNA …

Cultivated peanut (Arachis hypogaea) is an allotetraploid with closely related subgenomes
of a total size of∼ 2.7 Gb. This makes the assembly of chromosomal pseudomolecules very …

Cytosine methylation is a DNA modification generally associated with transcriptional
silencing. Factors that regulate methylation have been linked to human disease, yet how …

Transposable element (TE)-derived sequences are ubiquitous in most eukaryotic genomes
known to date. Because their expression and mobility can lead to genomic instability …

Recent technological advances have made it possible to decode DNA methylomes at single-
base-pair resolution under various physiological conditions. Many aberrant or differentially …

The draft genome of the moss model, Physcomitrella patens, comprised approximately 2000
unordered scaffolds. In order to enable analyses of genome structure and evolution we …

Background DNA methylation is an important feature of plant epigenomes, involved in the
formation of heterochromatin and affecting gene expression. Extensive variation of DNA …