[HTML][HTML] Worldwide prevalence of Lynch syndrome in patients with colorectal cancer: Systematic review and meta-analysis
Purpose Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC)
syndrome, with an estimated prevalence of 2% to 3% of CRC. A prevalence study is needed …
syndrome, with an estimated prevalence of 2% to 3% of CRC. A prevalence study is needed …
Validity of a two-antibody testing algorithm for mismatch repair deficiency testing in cancer; a systematic literature review and meta-analysis
Reflex mismatch repair immunohistochemistry (MMR IHC) testing for MLH1, PMS2, MSH2
and MSH6 is used to screen for Lynch syndrome. Recently MMR-deficiency (MMRd) has …
and MSH6 is used to screen for Lynch syndrome. Recently MMR-deficiency (MMRd) has …
Universal screening of both endometrial and colon cancers increases the detection of Lynch syndrome
T Adar, LH Rodgers, KM Shannon, M Yoshida, T Ma… - Cancer, 2018 - Wiley Online Library
BACKGROUND Lynch syndrome (LS) is the most common hereditary cause of colorectal
cancer (CRC) and endometrial cancer (EC). Screening of all CRCs for LS is currently …
cancer (CRC) and endometrial cancer (EC). Screening of all CRCs for LS is currently …
Colorectal Cancer in North-Eastern Iran: a retrospective, comparative study of early-onset and late-onset cases based on data from the Iranian hereditary colorectal …
Background The incidence rate of colorectal cancer (CRC) is increasing among patients
below 50 years of age. The reason for this is unclear, but could have to do with the fact that …
below 50 years of age. The reason for this is unclear, but could have to do with the fact that …
Differential expression of PD-L1 between primary and metastatic epithelial ovarian cancer and its clinico-pathological correlation
SK Parvathareddy, AK Siraj, IA Al-Badawi, A Tulbah… - Scientific Reports, 2021 - nature.com
Ovarian cancer (OC) is one of the most common gynecologic cancer, which has the worst
prognosis and highest mortality rate. The lack of curative treatment and the high relapse …
prognosis and highest mortality rate. The lack of curative treatment and the high relapse …
[HTML][HTML] Clinical, pathological, and molecular characteristics of CpG island methylator phenotype in colorectal cancer: a systematic review and meta-analysis
BACKGROUND: CpG island methylator phenotype (CIMP) tumors, comprising 20% of
colorectal cancers, are associated with female sex, age, right-sided location, and BRAF …
colorectal cancers, are associated with female sex, age, right-sided location, and BRAF …
Prevalence of Lynch syndrome and Lynch-like syndrome among patients with colorectal cancer in a Japanese hospital-based population
N Chika, H Eguchi, K Kumamoto… - Japanese journal of …, 2017 - academic.oup.com
Objective We investigated the prevalence of Lynch syndrome and Lynch-like syndrome
among Japanese colorectal cancer patients, as there have been no credible data from …
among Japanese colorectal cancer patients, as there have been no credible data from …
Global differences in the prevalence of the CpG island methylator phenotype of colorectal cancer
Abstract Background CpG Island Methylator Phenotype (CIMP) is an epigenetic phenotype
in CRC characterized by hypermethylation of CpG islands in promoter regions of tumor …
in CRC characterized by hypermethylation of CpG islands in promoter regions of tumor …
[HTML][HTML] Investigating the prevalence of pathogenic variants in Saudi Arabian patients with familial cancer using a multigene next generation sequencing panel
M AlHarbi, NA Mobark, WAR AlJabarat, H ElBardis… - Oncotarget, 2023 - ncbi.nlm.nih.gov
Family history is an important factor in determining hereditary cancer risk for many cancer
types. The emergence of next-generation sequencing (NGS) has expedited the discovery of …
types. The emergence of next-generation sequencing (NGS) has expedited the discovery of …
Colorectal cancer screening in the Middle East: what, why, who, when, and how?
A Shamseddine, L Chehade… - American Society of …, 2023 - ascopubs.org
The incidence of colorectal cancer (CRC) in the Middle East is increasing, especially among
those younger than 50 years. Risk factors including obesity, sedentary lifestyle, and dietary …
those younger than 50 years. Risk factors including obesity, sedentary lifestyle, and dietary …