[HTML][HTML] Systemic therapies for salivary gland adenoid cystic carcinoma

S Sahara, AE Herzog, JE Nör - American Journal of Cancer …, 2021 - ncbi.nlm.nih.gov
Adenoid cystic carcinoma (ACC) is a slow growing, but relentless cancer. Due to its rarity
and lack of understanding of its molecular etiology, no standard chemotherapy for ACC …

Salivary gland carcinoma: novel targets to overcome treatment resistance in advanced disease

L Di Villeneuve, IL Souza, FDS Tolentino… - Frontiers in …, 2020 - frontiersin.org
Salivary gland carcinomas (SGC) account for less than 5% of head and neck malignant
neoplasms, further subcategorized in over 20 histological subtypes. For the most part …

Management of salivary gland malignancy: ASCO guideline

JL Geiger, N Ismaila, B Beadle, JJ Caudell… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE To provide evidence-based recommendations for practicing physicians and
other healthcare providers on the management of salivary gland malignancy. METHODS …

Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma

AS Ho, A Ochoa, G Jayakumaran… - The Journal of …, 2019 - Am Soc Clin Investig
BACKGROUND Adenoid cystic carcinoma (ACC) is a rare malignancy arising in salivary
glands and other sites, characterized by high rates of relapse and distant spread …

Phase II study of lenvatinib in patients with progressive, recurrent or metastatic adenoid cystic carcinoma

V Tchekmedyian, EJ Sherman, L Dunn… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE Recurrent or metastatic adenoid cystic carcinoma (R/M ACC) is a malignant
neoplasm of predominantly salivary gland origin for which effective therapies are lacking …

Radiotherapy for salivary gland cancer: REFCOR recommendations by the formal consensus method

J Thariat, FR Ferrand, N Fakhry, C Even… - European annals of …, 2024 - Elsevier
Objective To determine the indications for radiotherapy in salivary gland cancer and to
specify the modalities and target radiation volumes. Material and methods The French …

Targeted therapy, chemotherapy, immunotherapy and novel treatment options for different subtypes of salivary gland cancer

SK Mueller, M Haderlein, S Lettmaier… - Journal of Clinical …, 2022 - mdpi.com
Surgical resection remains the first line treatment for salivary gland cancer (SGC). In the
case of locally advanced disease, surgery is followed by adjuvant radiotherapy. Surgical …

Oncolytic virus encoding a master pro-inflammatory cytokine interleukin 12 in cancer immunotherapy

HM Nguyen, K Guz-Montgomery, D Saha - Cells, 2020 - mdpi.com
Oncolytic viruses (OVs) are genetically modified or naturally occurring viruses, which
preferentially replicate in and kill cancer cells while sparing healthy cells, and induce anti …

Approaches to the management of metastatic adenoid cystic carcinoma

RH Lee, KC Wai, JW Chan, PK Ha, H Kang - Cancers, 2022 - mdpi.com
Simple Summary Patients with adenoid cystic carcinoma (ACC) often experience late distant
metastasis years after definitive therapy, most commonly to the lungs. Currently, there is little …

Patients with adenoid cystic carcinomas of the salivary glands treated with lenvatinib: activity and quality of life

LD Locati, D Galbiati, G Calareso, S Alfieri, S Singer… - Cancer, 2020 - Wiley Online Library
Background The treatment of patients with recurrent and/or metastatic (R/M) salivary gland
adenoid cystic carcinoma (ACC) remains an unmet need. Methods Patients with R/M …