Oncolytic viruses: newest frontier for cancer immunotherapy

MM Rahman, G McFadden - Cancers, 2021 - mdpi.com
Simple Summary Oncolytic viruses (OVs) are viruses that selectively target and kill cancer
cells while sparing normal ones. OVs are from diverse families of viruses, but naturally …

Virus-mediated cell-cell fusion

H Leroy, M Han, M Woottum, L Bracq… - International Journal of …, 2020 - mdpi.com
Cell-cell fusion between eukaryotic cells is a general process involved in many
physiological and pathological conditions, including infections by bacteria, parasites, and …

Oncolytic viruses: challenges and considerations in an evolving clinical landscape

UM Lauer, J Beil - Future Oncology, 2022 - Taylor & Francis
Despite advances in treatment, cancer remains a leading cause of death worldwide.
Although treatment strategies are continually progressing, cancers have evolved many …

Measles virus as an oncolytic immunotherapy

CE Engeland, G Ungerechts - Cancers, 2021 - mdpi.com
Simple Summary Measles virus is currently under investigation as an innovative cancer
treatment. The virus selectively replicates in and kills cancer cells. Furthermore, it can be …

Viral proteins recognized by different TLRs

R Zhou, L Liu, Y Wang - Journal of Medical Virology, 2021 - Wiley Online Library
Virus invasion activates the host's innate immune response, inducing the production of
numerous cytokines and interferons to eliminate pathogens. Except for viral DNA/RNA, viral …

Evolution and interspecies transmission of canine distemper virus—an outlook of the diverse evolutionary landscapes of a multi-host virus

J Duque-Valencia, N Sarute, XA Olarte-Castillo… - Viruses, 2019 - mdpi.com
Canine distemper virus (CDV) is a worldwide distributed virus which belongs to the genus
Morbillivirus within the Paramyxoviridae family. CDV spreads through the lymphatic …

Virological and immunological features of SARS-CoV-2-infected children who develop neutralizing antibodies

N Cotugno, A Ruggiero, F Bonfante, MR Petrara… - Cell reports, 2021 - cell.com
As the global COVID-19 pandemic progresses, it is paramount to gain knowledge on
adaptive immunity to SARS-CoV-2 in children to define immune correlates of protection …

Immunotherapeutic potential of TGF-β inhibition and oncolytic viruses

C Groeneveldt, T van Hall, SH van der Burg… - Trends in …, 2020 - cell.com
In cancer immunotherapy, a patient's own immune system is harnessed against cancer.
Immune checkpoint inhibitors release the brakes on tumor-reactive T cells and, therefore …

Redox control in the pathophysiology of influenza virus infection

KK Chen, M Minakuchi, K Wuputra, CC Ku, JB Pan… - BMC microbiology, 2020 - Springer
Triggered in response to external and internal ligands in cells and animals, redox
homeostasis is transmitted via signal molecules involved in defense redox mechanisms …

[HTML][HTML] Preexisting immunity: Barrier or bridge to effective oncolytic virus therapy?

C Groeneveldt, J van den Ende… - Cytokine & Growth Factor …, 2023 - Elsevier
Oncolytic viruses (OVs) represent a highly promising treatment strategy for a wide range of
cancers, by mediating both the direct killing of tumor cells as well as mobilization of …