Leishmaniasis: current status of vaccine development

E Handman - Clinical microbiology reviews, 2001 - Am Soc Microbiol
Leishmaniae are obligatory intracellular protozoa in mononuclear phagocytes. They cause a
spectrum of diseases, ranging in severity from spontaneously healing skin lesions to fatal …

[PDF][PDF] Orally effective drugs for kala-azar (visceral leishmaniasis): focus on miltefosine and sitamaquine

H Sangraula, KK Sharma, S Rijal, S Dwivedi… - J Assoc Physicians …, 2003 - academia.edu
Currently there are no effective orally administered drugs or visceral leishmaniasis or kala-
azar, a parasitic disease affecting about 0.5 million people a year, majority of whom are in …

Identification of Potent Chemotypes Targeting Leishmania major Using a High-Throughput, Low-Stringency, Computationally Enhanced, Small Molecule Screen

ER Sharlow, D Close, T Shun… - PLoS neglected …, 2009 - journals.plos.org
Patients with clinical manifestations of leishmaniasis, including cutaneous leishmaniasis,
have limited treatment options, and existing therapies frequently have significant untoward …

Leishmania tropica: cysteine proteases are essential for growth and pathogenicity

H Mahmoudzadeh-Niknam, JH McKerrow - Experimental parasitology, 2004 - Elsevier
Leishmania parasites are responsible for a diverse collection of diseases of humans and
other animals. Cysteine proteases are putative virulence factors of leishmania parasites …

Factors associated with treatmet failure of cutaneous leishmaniasis with meglumine antimoniate

AM Rodrigues, M Hueb, TARR Santos… - Revista da Sociedade …, 2006 - search.proquest.com
We investigated factors associated with treatment failure in the treatment of cutaneous
leishmaniasis with meglumine antimony in a reference service in Mato Grosso State. A …

Development of a fast agglutination screening test (FAST) for the detection of anti-Leishmania antibodies in dogs

H Schallig, GJ Schoone, EGM Beijer, CCM Kroon… - Veterinary …, 2002 - Elsevier
A fast agglutination screening test (FAST) for the detection of anti-Leishmania antibodies in
serum samples from dogs with visceral leishmaniosis was developed. The test is based on …

[HTML][HTML] Fatores associados ao insucesso do tratamento da leishmaniose cutânea com antimoniato de meglumina

AM Rodrigues, M Hueb, TARR Santos… - Revista da Sociedade …, 2006 - SciELO Brasil
Foram investigados os fatores associados ao insucesso do tratamento da leishmaniose
cutânea com antimoniato de meglumina num serviço de referência para leishmanioses, em …

Leishmaniasis. A review

DS Vera-Izaguirre, E Vega-Memije… - … Cosmética, Médica Y …, 2006 - medigraphic.com
Background: Leishmaniasis constitutes a variety of human diseases ranging in severity from
a spontaneously healing skin ulcer to an overwhelming visceral disease. Leishmaniasis …

Community views on cutaneous leishmaniasis in Istalif, Afghanistan: implications for treatment and prevention

CC Stewart, WR Brieger - International quarterly of …, 2009 - journals.sagepub.com
Afghanistan currently has the world's largest outbreak of Cutaneous Leishmaniasis with
more than 9% of the population (270,000) of Kabul affected. Transmitted through the bite of …

Variable Degree of Alternative Complement Pathway-Mediated Hemolysis in Indian Visceral Leishmaniasis Induced by Differential Expression of 9-O-Acetylated …

AK Chava, M Chatterjee, V Sharma… - Journal of Infectious …, 2004 - academic.oup.com
Background. Increased expression of linkage-specific 9-O-acetylated sialoglycans (9-O-
AcSGs) has been demonstrated on erythrocytes from patients with visceral leishmaniasis …