Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

Among numerous solvents available for chemical transformations, 1, 1, 1, 3, 3, 3-hexafluoro-
2-propanol (popularly known as HFIP) has attracted enough attention of the scientific …

Transition metal-catalysed functionalizations of inert C–H bonds to construct C–C bonds
represent an ideal route in the synthesis of valuable organic molecules. Fine tuning of …

The selective functionalization of C–H bonds is an extremely important topic in present-day
organic synthesis, as it utilizes the most abundant portion of a molecule as a tool for …

The metal-catalyzed “cascade C–H activation/annulation” is a highly promising approach to
the construction of aromatic and heteroaromatic compounds. In this context, Pd-complexes …

The selective functionalization of C (sp3)− H bonds using transition‐metal catalysis is
among the more attractive transformations of modern synthetic chemistry. In addition to its …

Carboxylic acids are highly abundant in bioactive molecules. In this study, we describe the
late-stage β-C (sp3)–H deuteration of free carboxylic acids. On the basis of the finding that C …

An efficient method for the synthesis of bicyclic spirodiamine molecules via β-C (sp3)–H
bond activation of aliphatic amides, followed by cyclization with maleimides, has been …

Pd-catalysed C–H functionalisation of free carboxylic acids has drawn significant attention
over the last few years due to the predominance of carboxylic acid moieties in …

A novel method by a one-step introduction of axial chirality and sterically hindered group
has been developed for facile synthesis of axially chiral styrene-type carboxylic acids. With …