N-Acetylcysteine and its immunomodulatory properties in humans and domesticated animals
S Tieu, A Charchoglyan, L Paulsen… - Antioxidants, 2023 - mdpi.com
N-acetylcysteine (NAC), an acetylated derivative of the amino acid L-cysteine, has been
widely used as a mucolytic agent and antidote for acetaminophen overdose since the 1960s …
widely used as a mucolytic agent and antidote for acetaminophen overdose since the 1960s …
On the role of paraoxonase-1 and chemokine ligand 2 (CC motif) in metabolic alterations linked to inflammation and disease. A 2021 update
J Camps, H Castañé, E Rodríguez-Tomàs… - Biomolecules, 2021 - mdpi.com
Infectious and many non-infectious diseases share common molecular mechanisms. Among
them, oxidative stress and the subsequent inflammatory reaction are of particular note …
them, oxidative stress and the subsequent inflammatory reaction are of particular note …
Dengue virus targets Nrf2 for NS2B3-mediated degradation leading to enhanced oxidative stress and viral replication
M Ferrari, A Zevini, E Palermo, M Muscolini… - Journal of …, 2020 - Am Soc Microbiol
Dengue virus (DENV) is a mosquito-borne virus that infects upward of 300 million people
annually and has the potential to cause fatal hemorrhagic fever and shock. While the …
annually and has the potential to cause fatal hemorrhagic fever and shock. While the …
Paraoxonases and infectious diseases
J Camps, S Iftimie, A Garcia-Heredia, A Castro… - Clinical …, 2017 - Elsevier
Abstract The paraoxonases (PON1, PON2 and PON3) are an enzyme family with a high
structural homology. All of them have lactonase activity and degrade lipid peroxides in …
structural homology. All of them have lactonase activity and degrade lipid peroxides in …
Oxidative stress response in the pathogenesis of dengue virus virulence, disease prognosis and therapeutics: an update
AB Pillai, KR Muthuraman, V Mariappan, SS Belur… - Archives of …, 2019 - Springer
Dengue virus (DENV) is a mosquito-borne arbovirus that causes febrile illness and can lead
to a potentially lethal disease. The mechanism of disease pathogenesis is not completely …
to a potentially lethal disease. The mechanism of disease pathogenesis is not completely …
Amelioration of oxidative stress using N‐acetylcysteine in canine parvoviral enteritis
C Gaykwad, J Garkhal, GE Chethan… - Journal of veterinary …, 2018 - Wiley Online Library
Previously, antioxidants have not been evaluated for treatment of parvoviral diarrhea in
dogs. In this study, antioxidant potential of N‐acetylcysteine (NAC) in dogs infected with …
dogs. In this study, antioxidant potential of N‐acetylcysteine (NAC) in dogs infected with …
Crocetin improves dengue virus-induced liver injury
GP Sreekanth, A Chuncharunee, P Yenchitsomanus… - Viruses, 2020 - mdpi.com
Dengue virus (DENV) infection is one of the most widespread mosquito-borne viral
infections. Liver injury is commonly observed in severe DENV infection, and the present …
infections. Liver injury is commonly observed in severe DENV infection, and the present …
Paraoxonase-1: How a xenobiotic detoxifying enzyme has become an actor in the pathophysiology of infectious diseases and cancer
Both infectious and non-infectious diseases can share common molecular mechanisms,
including oxidative stress and inflammation. External factors, such as bacterial or viral …
including oxidative stress and inflammation. External factors, such as bacterial or viral …
Clinical Relevance of Oxidative Stress Biomarkers in Human Flavivirus Infections as Predictors of Disease Progression and Severity
M Van Herreweghe, T De Bruyne… - Reviews in Medical …, 2024 - Wiley Online Library
Several Flaviviridae constitute an emerging threat to global health because of their
continuing spread and the expansion of vector habitats, largely driven by climate change …
continuing spread and the expansion of vector habitats, largely driven by climate change …
[HTML][HTML] A systematic review of observational studies on oxidative/nitrosative stress involvement in dengue pathogenesis
R Castro, HS Pinzón, N Alvis-Guzman - Colombia Medica, 2015 - scielo.org.co
Objective: Our objective was to systematically review the published observational research
related to the role of oxidative-nitrosative stress in pathogenesis of dengue. Methods: We …
related to the role of oxidative-nitrosative stress in pathogenesis of dengue. Methods: We …