Environmental influences on the epigenome: exposure-associated DNA methylation in human populations
EM Martin, RC Fry - Annual review of public health, 2018 - annualreviews.org
DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …
environmental exposures. To date, numerous studies have detailed the manner by which …
Epigenetics and human obesity
Background: Recent technological advances in epigenome profiling have led to an
increasing number of studies investigating the role of the epigenome in obesity. There is …
increasing number of studies investigating the role of the epigenome in obesity. There is …
Sensitive periods for the effect of childhood adversity on DNA methylation: results from a prospective, longitudinal study
Background Exposure to early-life adversity is known to predict DNA methylation (DNAm)
patterns that may be related to psychiatric risk. However, few studies have investigated …
patterns that may be related to psychiatric risk. However, few studies have investigated …
Life course socioeconomic status and DNA methylation in genes related to stress reactivity and inflammation: the multi-ethnic study of atherosclerosis
Epigenetic changes, such as DNA methylation, have been hypothesized to provide a link
between the social environment and disease development. The purpose of this study was to …
between the social environment and disease development. The purpose of this study was to …
[HTML][HTML] Use of an exposome approach to understand the effects of exposures from the natural, built, and social environments on cardio-vascular disease onset …
Obesity, diabetes, and hypertension have increased by epidemic proportions in recent years
among African Americans in comparison to Whites resulting in significant adverse …
among African Americans in comparison to Whites resulting in significant adverse …
DNA methylation-based variation between human populations
F Kader, M Ghai - Molecular genetics and genomics, 2017 - Springer
Several studies have proved that DNA methylation affects regulation of gene expression and
development. Epigenome-wide studies have reported variation in methylation patterns …
development. Epigenome-wide studies have reported variation in methylation patterns …
[HTML][HTML] Associations between indicators of socioeconomic position and DNA methylation: a scoping review
Background Socioeconomic position (SEP) is a major determinant of health across the life
course. Yet, little is known about the biological mechanisms explaining this relationship. One …
course. Yet, little is known about the biological mechanisms explaining this relationship. One …
[HTML][HTML] Meta-analysis of human methylation data for evidence of sex-specific autosomal patterns
Background Several individual studies have suggested that autosomal CpG methylation
differs by sex both in terms of individual CpG sites and global autosomal CpG methylation …
differs by sex both in terms of individual CpG sites and global autosomal CpG methylation …
[HTML][HTML] Dynamic Alu Methylation during Normal Development, Aging, and Tumorigenesis
Y Luo, X Lu, H Xie - BioMed research international, 2014 - hindawi.com
DNA methylation primarily occurs on CpG dinucleotides and plays an important role in
transcriptional regulations during tissue development and cell differentiation. Over 25% of …
transcriptional regulations during tissue development and cell differentiation. Over 25% of …
Biological embedding of early‐life exposures and disease risk in humans: a role for DNA methylation
CA Demetriou, K van Veldhoven… - European journal of …, 2015 - Wiley Online Library
Background Following wider acceptance of 'the thrifty phenotype'hypothesis and the
convincing evidence that early‐life exposures can influence adult health even decades after …
convincing evidence that early‐life exposures can influence adult health even decades after …