Terpenoids' anti-cancer effects: Focus on autophagy
Terpenoids are the largest class of natural products, most of which are derived from plants.
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …
Amongst their numerous biological properties, their anti-tumor effects are of interest for they …
Platycodon grandiflorum (Jacq.) A. DC.: A review of phytochemistry, pharmacology, toxicology and traditional use
S Zhang, X Chai, G Hou, F Zhao, Q Meng - Phytomedicine, 2022 - Elsevier
Abstract Background The traditional Chinese medicine Platycodon grandiflorum (Jacq.) A.
DC.(PG, balloon flower) has medicinal and culinary value. It consists of a variety of chemical …
DC.(PG, balloon flower) has medicinal and culinary value. It consists of a variety of chemical …
Saponins from Chinese medicines as anticancer agents
Saponins are glycosides with triterpenoid or spirostane aglycones that demonstrate various
pharmacological effects against mammalian diseases. To promote the research and …
pharmacological effects against mammalian diseases. To promote the research and …
Killing cancer with platycodin D through multiple mechanisms
M Khan, A Maryam, H Zhang… - Journal of cellular and …, 2016 - Wiley Online Library
Cancer is a multi‐faceted disease comprised of a combination of genetic, epigenetic,
metabolic and signalling aberrations which severely disrupt the normal homoeostasis of cell …
metabolic and signalling aberrations which severely disrupt the normal homoeostasis of cell …
Ophiopogon japonicus and its active compounds: A review of potential anticancer effects and underlying mechanisms
Abstract Background Ophiopogon japonicus (Thunb.) Ker Gawl., a well-known Chinese
herb, has been used in traditional Chinese medicine for thousands of years. Extensive in …
herb, has been used in traditional Chinese medicine for thousands of years. Extensive in …
Bioactive platycodins from Platycodonis Radix: Phytochemistry, pharmacological activities, toxicology and pharmacokinetics
LL Zhang, MY Huang, Y Yang, MQ Huang, JJ Shi… - Food chemistry, 2020 - Elsevier
Platycodonis Radix, the root of Platycodon grandiflorum (Jacq.) A. DC., is a well-known
edible herbal medicine. It is a common vegetable used for the preparation of side dish …
edible herbal medicine. It is a common vegetable used for the preparation of side dish …
Non-apoptotic cell death in malignant tumor cells and natural compounds
J Ye, R Zhang, F Wu, L Zhai, K Wang, M Xiao, T Xie… - Cancer letters, 2018 - Elsevier
Traditional cancer therapy is mainly targeting on enhancing cell apoptosis, however, it is
well established that many cancer cells are chemo-resistant and defective in apoptosis …
well established that many cancer cells are chemo-resistant and defective in apoptosis …
Recent progress in understanding the action of natural compounds at novel therapeutic drug targets for the treatment of liver cancer
Y Zheng, W Zhang, L Xu, H Zhou, M Yuan… - Frontiers in …, 2022 - frontiersin.org
Liver cancer is the third most common cause of cancer-related death following lung and
stomach cancers. As a highly lethal disease, liver cancer is diagnosed frequently in less …
stomach cancers. As a highly lethal disease, liver cancer is diagnosed frequently in less …
Platycodin D inhibits autophagy and increases glioblastoma cell death via LDLR upregulation
Targeting autophagy is a promising therapeutic approach in cancer therapy. Here, we
screened 30 traditional herbal medicines to identify novel autophagy regulators and found …
screened 30 traditional herbal medicines to identify novel autophagy regulators and found …
Distribution, biotransformation, pharmacological effects, metabolic mechanism and safety evaluation of Platycodin D: A comprehensive review
Q Li, T Yang, S Zhao, Q Zheng, Y Li… - Current Drug …, 2022 - ingentaconnect.com
Platycodonis Radix (Jiegeng), the dried root of Platycodon grandiflorum, is a traditional herb
used as both medicine and food. Its clinical application for the treatment of cough, phlegm …
used as both medicine and food. Its clinical application for the treatment of cough, phlegm …