Cross-feeding in the gut microbiome: ecology and mechanisms
EJ Culp, AL Goodman - Cell host & microbe, 2023 - cell.com
Microbial communities are shaped by positive and negative interactions ranging from
competition to mutualism. In the context of the mammalian gut and its microbial inhabitants …
competition to mutualism. In the context of the mammalian gut and its microbial inhabitants …
[HTML][HTML] Microbiome-based interventions to modulate gut ecology and the immune system
The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …
Statistically learning the functional landscape of microbial communities
Microbial consortia exhibit complex functional properties in contexts ranging from soils to
bioreactors to human hosts. Understanding how community composition determines …
bioreactors to human hosts. Understanding how community composition determines …
Microbial community-scale metabolic modelling predicts personalized short-chain fatty acid production profiles in the human gut
N Quinn-Bohmann, T Wilmanski, KR Sarmiento… - Nature …, 2024 - nature.com
Microbially derived short-chain fatty acids (SCFAs) in the human gut are tightly coupled to
host metabolism, immune regulation and integrity of the intestinal epithelium. However, the …
host metabolism, immune regulation and integrity of the intestinal epithelium. However, the …
In vitro interaction network of a synthetic gut bacterial community
AS Weiss, AG Burrichter, AC Durai Raj… - The ISME …, 2022 - academic.oup.com
A key challenge in microbiome research is to predict the functionality of microbial
communities based on community membership and (meta)-genomic data. As central …
communities based on community membership and (meta)-genomic data. As central …
Assembling symbiotic bacterial species into live therapeutic consortia that reconstitute microbiome functions
RA Oliveira, EG Pamer - Cell Host & Microbe, 2023 - cell.com
Increasing experimental evidence suggests that administering live commensal bacterial
species can optimize microbiome composition and lead to reduced disease severity and …
species can optimize microbiome composition and lead to reduced disease severity and …
Synthetic microbial communities (SynComs) of the human gut: design, assembly, and applications
The human gut harbors native microbial communities, forming a highly complex ecosystem.
Synthetic microbial communities (SynComs) of the human gut are an assembly of …
Synthetic microbial communities (SynComs) of the human gut are an assembly of …
Short-chain fatty acids: linking diet, the microbiome and immunity
The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial
metabolites and their availability in the gut and other organs is determined by environmental …
metabolites and their availability in the gut and other organs is determined by environmental …
Massively parallel single-cell sequencing of diverse microbial populations
Single-cell genetic heterogeneity is ubiquitous in microbial populations and an important
aspect of microbial biology; however, we lack a broadly applicable and accessible method …
aspect of microbial biology; however, we lack a broadly applicable and accessible method …
The community-function landscape of microbial consortia
Quantitatively linking the composition and function of microbial communities is a major
aspiration of microbial ecology. Microbial community functions emerge from a complex web …
aspiration of microbial ecology. Microbial community functions emerge from a complex web …