Neurobiology, clinical presentation, and treatment of methamphetamine use disorder: a review

MP Paulus, JL Stewart - JAMA psychiatry, 2020 - jamanetwork.com
Importance The prevalence of and mortality associated with methamphetamine use has
doubled during the past 10 years. There is evidence suggesting that methamphetamine use …

[HTML][HTML] Sex differences in methamphetamine use disorder perused from pre-clinical and clinical studies: Potential therapeutic impacts

AP Daiwile, S Jayanthi, JL Cadet - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Methamphetamine (METH) use, and misuse are associated with severe socioeconomic
consequences. METH users develop tolerance, lose control over drug taking behaviors, and …

Effects of mirtazapine for methamphetamine use disorder among cisgender men and transgender women who have sex with men: a placebo-controlled randomized …

PO Coffin, GM Santos, J Hern, E Vittinghoff… - JAMA …, 2020 - jamanetwork.com
Importance Methamphetamine use is increasingly prevalent and associated with HIV
transmission. A previous phase 2a study of mirtazapine demonstrated reductions in …

Distinct suppressing effects of deep brain stimulation in the orbitofrontal cortex on the development, extinction, and reinstatement of methamphetamine-seeking …

M Fattahi, K Eskandari, E Riahi, R Khosrowabadi… - Life Sciences, 2023 - Elsevier
Aims The orbitofrontal cortex (OFC) is implicated in compulsive drug-seeking and relapse,
the characteristics that result in addiction treatment failure. Structural and functional …

Cannabidiol treatment might promote resilience to cocaine and methamphetamine use disorders: a review of possible mechanisms

C Calpe-López, MP García-Pardo, MA Aguilar - Molecules, 2019 - mdpi.com
Currently, there are no approved pharmacotherapies for addiction to cocaine and other
psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a …

Characterising the increasing prevalence of crystal methamphetamine use in Vancouver, Canada, from 2006–2017: A gender‐based analysis

P Bach, K Hayashi, MJ Milloy, E Nosova… - Drug and alcohol …, 2020 - Wiley Online Library
Introduction Methamphetamine use is increasing in North America and is associated with
numerous negative health effects and social harms. As drug‐related harms are often …

Cannabidiol treatment reduces the motivation to self-administer methamphetamine and methamphetamine-primed relapse in rats

GL Hay, SJ Baracz, NA Everett… - Journal of …, 2018 - journals.sagepub.com
Background: Methamphetamine is an addictive stimulant that can cause many adverse
physical, psychological and psychosocial effects. Preliminary evidence shows cannabidiol …

Goofballing of opioid and methamphetamine: The science behind the deadly cocktail

HM Hazani, I Naina Mohamed, M Muzaimi… - Frontiers in …, 2022 - frontiersin.org
Globally, millions of people suffer from various substance use disorders (SUD), including
mono-and polydrug use of opioids and methamphetamine. Brain regions such as the …

The neurobiological mechanisms of physical exercise in methamphetamine addiction

APD Morais, IR Pita, CA Fontes‐Ribeiro… - CNS neuroscience & …, 2018 - Wiley Online Library
Methamphetamine (METH) is the primary drug within amphetamine‐type stimulants which
are the second most abused group of drugs worldwide. There is no pharmacological …

The vagus nerve mediates the suppressing effects of peripherally administered oxytocin on methamphetamine self-administration and seeking in rats

NA Everett, AJ Turner, PA Costa, SJ Baracz… - …, 2021 - nature.com
The neuropeptide oxytocin has emerged as a promising pharmacotherapy for
methamphetamine (METH) addiction, and clinical trials of intranasal oxytocin are underway …