Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Melatonin is an ancient molecule that can be traced back to the origin of life. Melatonin's
initial function was likely that as a free radical scavenger. Melatonin presumably evolved in …

Mitochondria are best known for their role in the generation of ATP by aerobic respiration.
Yet, research in the past half century has shown that they perform a much larger suite of …

Melatonin is a ubiquitous indolamine, largely investigated for its key role in the regulation of
several physiological processes in both animals and plants. In the last century, it was …

Bacteria influence eukaryotic biology as parasitic, commensal or beneficial symbionts. Aside
from these organismal interactions, bacteria have also been important sources of new …

Many physiological changes occur in response to endurance exercise in order to adapt to
the increasing energy needs, mitochondria biogenesis, increased reactive oxygen species …

Significance: Oxidative stress is thought to account for aberrant redox homeostasis and
contribute to aging and disease. However, more often than not, administration of …

Mitochondria have specialized ribosomes that have diverged from their bacterial and
cytoplasmic counterparts. We have solved the structure of the yeast mitoribosomal large …

Melatonin is a phylogenetically ancient molecule. It is ubiquitously present in almost all
organisms from primitive photosynthetic bacteria to humans. Its original primary function is …

Horizontal gene transfer (HGT; also known as lateral gene transfer) has had an important
role in eukaryotic genome evolution, but its importance is often overshadowed by the greater …